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roxindole
Known as:
roxindol
National Institutes of Health
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Related topics
Related topics
3 relations
Narrower (1)
EMD 49980
Broader (2)
Indoles
Pyridines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Endocrine characterization of the new dopamine autoreceptor agonist roxindole.
K. Wiedemann
,
M. Kellner
Experimental and clinical endocrinology
2009
Corpus ID: 13584071
Roxindole (5-Hydroxy-3-(4-phenyl-1,2,3,6-tetrahydropyridil-(1)-butyl)-indol) is a newly developed compound with a high dopamine…
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2005
2005
Roxindole, a dopamine autoreceptor agonist, in the treatment of major depression
G. Gründer
,
Hermann Wetzel
,
E. Hammes
,
O. Benkert
Psychopharmacology
2005
Corpus ID: 8154586
Roxindole is a potent autoreceptor-“selective” dopamine agonist originally developed for the treatment of schizophrenic syndromes…
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2005
2005
Roxindole, a potential antidepressant I. Effect on the dopamine system
J. Maj
,
K. Kotodziejczyk
,
Z. Rogóż
,
G. Skuza
Journal of neural transmission
2005
Corpus ID: 33701841
SummaryRoxindole (EMD 49980, 5-hydroxy-3-[4-(4-phenyl-1,2,3,6-tetrahydropyridyl(1))-butyl(1)]-indole mesylate), a selective…
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2004
2004
Opioid and monoamine systems mediate the discriminative stimulus of tramadol in rats.
M. Filip
,
K. Wydra
,
S. Inan
,
M. Dziedzicka-Wasylewska
,
E. Przegaliński
European Journal of Pharmacology
2004
Corpus ID: 29360337
1999
1999
Involvement of dopamine D2 and 5-HT1A receptors in roxindole-induced antinociception.
I. Ninan
,
S. Kulkarni
Indian journal of experimental biology
1999
Corpus ID: 36455531
Roxindole, a DA D2 receptor agonist (2-16 mg/kg) produced dose-dependent increase in percentage antinociception. The effect which…
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1995
1995
Binding properties of the naturally occurring human 5-HT1A receptor variant with the Ile28Val substitution in the extracellular domain
M. Brüss
,
M. Bühlen
,
M. Göthert
,
H. Bönisch
,
J. Erdmann
Naunyn-Schmiedeberg's Archives of Pharmacology
1995
Corpus ID: 24090339
The cDNA from a schizophrenic patient heterozygous for a mutation of the 5-HT1A receptor gene was used to clone the variant and…
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1994
1994
Roxindole, a dopamine autoreceptor agonist, in the treatment of positive and negative schizophrenic symptoms.
H. Wetzel
,
A. Hillert
,
G. Gründer
,
O. Benkert
American Journal of Psychiatry
1994
Corpus ID: 46395408
Twenty schizophrenic inpatients with either predominantly positive or predominantly negative symptoms were treated with the…
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1994
1994
Treatment of prolactinoma patients with the new non-ergot dopamine agonist roxindol: first results
C. Jaspers
,
G. Benker
,
D. Reinwein
Clinical Investigation
1994
Corpus ID: 532184
We studied the effects of the new non-ergot D2-dopamine agonist roxindol for the treatment of human prolactinomas. Roxindol is a…
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Review
1993
Review
1993
Dopamine autoreceptor agonists in the treatment of schizophrenic disorders
H. Wetzel
,
O. Benkert
Progress in Neuro-psychopharmacology and…
1993
Corpus ID: 28490384
1991
1991
Antipsychotic Efficacy of the Dopaminergic Autoreceptor Agonist EMD 49980 (Roxindol)
A. Klimke
,
E. Klieser
Pharmacopsychiatry
1991
Corpus ID: 38616816
EMD 49980 is a dopamine agonist with selective affinity to dopamine autoreceptors. Following pharmacological findings in animal…
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