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rosuvastatin

Known as: (3R,5S,6e)-7-(4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid, (3R,5S,6e)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid 
A statin with antilipidemic and potential antineoplastic activities. Rosuvastatin selectively and competitively binds to and inhibits hepatic… 
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (2)

CrestorZD4522
NCIt Antineoplastic Agent TerminologyRosuvastatin ZincRosuvastatin calciumRosuvastatin calcium 10 MG Oral Tablet [Crestor]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Ticagrelor and Rosuvastatin Have Additive Cardioprotective Effects via Adenosine
BackgroundTicagrelor inhibits the equilibrative-nucleoside-transporter-1 and thereby, adenosine cell re-uptake. Ticagrelor limits… 
Highly Cited
2009
Highly Cited
2009
Influence of Short-term Rosuvastatin Therapy on Endothelial Progenitor Cells and Endothelial Function
Endothelial progenitor cells maintain endothelium integrity by replacing injured endothelial cells. Cholesterol-lowering promotes… 
Highly Cited
2007
Highly Cited
2007
Double-blind, randomized, placebo-controlled study of high-dose HMG CoA reductase inhibitor therapy on ventricular remodeling, pro-inflammatory cytokines and neurohormonal parameters in patients with…
Review
2007
Review
2007
Role of C-reactive protein in coronary risk reduction: focus on primary prevention.
Review
2006
Review
2006
Statins: potential new indications in inflammatory conditions.
Highly Cited
2006
Highly Cited
2006
Switching statins
Using generic simvastatin as first line could save £2bn over five years in England 
Highly Cited
2005
Highly Cited
2005
Current Controlled Trials in Cardiovascular Medicine
  • 2005
  • Corpus ID: 1637962
Review
2005
Review
2005
Review of primary and secondary prevention trials with lovastatin, pravastatin, and simvastatin.
Highly Cited
2003
Highly Cited
2003
Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin
1. The liver is the target organ for the lipid-regulating effect of rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A… 
Review
2002
Review
2002
Managing dyslipidemia in the high-risk patient.
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