rosuvastatin

Known as: (3R,5S,6e)-7-(4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid, (3R,5S,6e)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid 
A statin with antilipidemic and potential antineoplastic activities. Rosuvastatin selectively and competitively binds to and inhibits hepatic… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Recent studies have shown that overweight and obesity play an important role in the development of osteoarthritis (OA). However… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Aortic stenosis (AS) is an active process with similarities to atherosclerosis. The objective of this study was to… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Statins reduce the incidence of cardiovascular events in patients at high cardiovascular risk. However, a benefit of… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Statins lower high-sensitivity C-reactive protein (hsCRP) and cholesterol concentrations, and hypothesis generating… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Controversy persists regarding the extent of shared pathways between arterial and venous thrombosis and whether… (More)
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Highly Cited
2009
Highly Cited
2009
 
Is this relevant?
Highly Cited
2007
Highly Cited
2007
OBJECTIVES The objective of this study was to test the effect of a 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase… (More)
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Highly Cited
2007
Highly Cited
2007
CONTEXT Atherosclerosis is often advanced before symptoms appear and it is not clear whether treatment is beneficial in middle… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or statins, target liver HMG-CoA and… (More)
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Highly Cited
2003
Highly Cited
2003
The primary objective of this 6-week, parallel-group, open-label, randomized, multicenter trial was to compare rosuvastatin with… (More)
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