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rosuvastatin

Known as: (3R,5S,6e)-7-(4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid, (3R,5S,6e)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid 
A statin with antilipidemic and potential antineoplastic activities. Rosuvastatin selectively and competitively binds to and inhibits hepatic… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Policy Points: Our study indicates that there are opportunities for cost savings in generic drug markets in Europe and the United… Expand
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Highly Cited
2010
Highly Cited
2010
Background— Aortic stenosis (AS) is an active process with similarities to atherosclerosis. The objective of this study was to… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Statins reduce the incidence of cardiovascular events in patients at high cardiovascular risk. However, a benefit of… Expand
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Highly Cited
2009
Highly Cited
2009
ABSTRACTPrevious studies have shown that statin therapy reduces high-sensitivity C-reactive protein levels as well as cholesterol… Expand
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Highly Cited
2009
Highly Cited
2008
Highly Cited
2008
BACKGROUND Increased levels of the inflammatory biomarker high-sensitivity C-reactive protein predict cardiovascular events… Expand
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Highly Cited
2008
Highly Cited
2008
Summary Background Large observational studies, small prospective studies and post-hoc analyses of randomised clinical trials… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Patients with systolic heart failure have generally been excluded from statin trials. Acute coronary events are… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or statins, target liver HMG-CoA and… Expand
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Highly Cited
2003
Highly Cited
2003
The primary objective of this 6-week, parallel-group, open-label, randomized, multicenter trial was to compare rosuvastatin with… Expand
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