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rolapitant

Known as: 1,7-diazaspiro(4.5)decan-2-one, 8-(((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-, (5S,8S)- 
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Chemotherapy induced nausea and vomiting is the among most feared and debilitating adverse events experienced by the cancer… 
2018
2018
Purpose: Prevention of chemotherapy-induced nausea and vomiting (CINV) is essential to preserve quality of life in cancer… 
2017
2017
The FDA has approved rolapitant injectable emulsion in combination with other antiemetics in adults to prevent delayed… 
2017
2017
The invention discloses a method for synthesizing a rolapitant intermediate. The method comprises a recrystallization method for… 
Review
2017
Review
2017
Objective: The objective of this selective EBM review is to determine whether or not rolapitant is safe and effective in reducing… 
Review
2017
Review
2017
Neurokinin-1 receptor antagonist, 5-hydroxytryptamine-3 RA, and dexamethasone combination therapy is standard of care for the… 
2017
2017
Rolapitant plus 5-HT3 receptor antagonist and dexamethasone is well tolerated and more effectively controls chemotherapy-induced… 
Review
2014
Review
2014
Chemotherapy-induced nausea and vomiting (CINV) has long been one of the most troublesome adverse effects of chemotherapy… 
2014
2014
ABSTRACT Aim: Rolapitant is a highly selective competitive long acting NK-1 receptor antagonist that demonstrated safety and…