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rolapitant
Known as:
1,7-diazaspiro(4.5)decan-2-one, 8-(((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-, (5S,8S)-
National Institutes of Health
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Related topics
Related topics
4 relations
Breast Cancer Resistance Protein Inhibitors [MoA]
rolapitant 90 MG Oral Tablet [Varubi]
rolapitant hydrochloride
Narrower (1)
Varubi
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abstract P6-11-18: Ten year trends in antiemetic prescribing in cancer patients receiving highly emetogenic chemotherapy (HEC)
C. O'Sullivan
,
H. V. Houten
,
+6 authors
K. Ruddy
2018
Corpus ID: 80586216
Purpose: Prevention of chemotherapy-induced nausea and vomiting (CINV) is essential to preserve quality of life in cancer…
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2017
2017
Method for synthesizing rolapitant intermediate
袁伟
,
张翔
,
+5 authors
杜伟
2017
Corpus ID: 139363011
The invention discloses a method for synthesizing a rolapitant intermediate. The method comprises a recrystallization method for…
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2017
2017
FDA Approves Rolapitant for Delayed CINV
B. Furlow
2017
Corpus ID: 182122616
The FDA has approved rolapitant injectable emulsion in combination with other antiemetics in adults to prevent delayed…
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Review
2017
Review
2017
Is Rolapitant Effective in Reducing the Incidence of Chemotherapy-Induced Nausea and Vomiting (CINV) in Patients Receiving Emetogenic Chemotherapy?
Brandon E Eberts
2017
Corpus ID: 86811944
Objective: The objective of this selective EBM review is to determine whether or not rolapitant is safe and effective in reducing…
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Review
2017
Review
2017
Injectable Emulsion Admixed with Intravenous Palonosetron Hydrochloride
George Wu
,
S. Yeung
,
PharmD Frank Chen
2017
Corpus ID: 4127772
Neurokinin-1 receptor antagonist, 5-hydroxytryptamine-3 RA, and dexamethasone combination therapy is standard of care for the…
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2017
2017
Rolapitant-Based Antiemetic Combination Improves CINV Symptoms
B. Furlow
2017
Corpus ID: 217078494
Rolapitant plus 5-HT3 receptor antagonist and dexamethasone is well tolerated and more effectively controls chemotherapy-induced…
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2016
2016
Erratum: Efficacy of the neurokinin‐1 receptor antagonist rolapitant in preventing nausea and vomiting in patients receiving carboplatin‐based chemotherapy
Cancer
2016
Corpus ID: 52308888
2016
2016
FDA approves rolapitant to prevent chemotherapy-induced nausea and vomiting
Daniel S. Raccuia
,
Pharmd Candidate
,
L. Holle
,
Pharmd
,
Bcop
,
Fhopa
2016
Corpus ID: 77747458
Rolapitant is a novel NK1 receptor antagonist that maintains >90% receptor binding up to five days after a single 180-mg dose.
Review
2014
Review
2014
New data in emerging treatment options for chemotherapy-induced nausea and vomiting in clinical practice: general discussion.
Rugo Hs
,
N. Rm
Clinical advances in hematology & oncology : H&O
2014
Corpus ID: 37123376
Chemotherapy-induced nausea and vomiting (CINV) has long been one of the most troublesome adverse effects of chemotherapy…
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2014
2014
LBA47_PRPHASE 3 (P04832) TRIAL RESULTS FOR ROLAPITANT, A NOVEL NK-1 RECEPTOR ANTAGONIST, IN THE PREVENTION OF CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING (CINV) IN PATIENTS RECEIVING CISPLATIN-BASED…
M. Chasen
,
A. Poma
,
M. Hedley
,
R. Martell
,
C. Gridelli
2014
Corpus ID: 73105288
ABSTRACT Aim: Rolapitant is a highly selective competitive long acting NK-1 receptor antagonist that demonstrated safety and…
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