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rolapitant hydrochloride

Known as: Rolapitant Monohydrochloride Monohydrate, 1,7-Diazaspiro(4.5)decan-2-one, 8-(((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-, Monohydrochloride, Monohydrate, (5S,8S)-, Rolapitant HCl 
The hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with… 
National Institutes of Health

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SCH 619734Varubi
rolapitantrolapitant 90 MG Oral Tablet [Varubi]

Papers overview

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2018
2018
Absorption, metabolism, and excretion of the antiemetic rolapitant, a selective neurokinin-1 receptor antagonist, in healthy male subjects
SummaryRolapitant is a neurokinin-1 receptor antagonist that is approved in combination with other antiemetic agents in adults… 
2018
2018
Compatibility and Stability of VARUBI (Rolapitant) Injectable Emulsion Admixed with Intravenous Palonosetron Hydrochloride Injection and Dexamethasone Sodium Phosphate Injection.
Prophylaxis or therapy with a combination of a neurokinin 1 (NK-1) receptor antagonist (RA), a 5-hydroxytryptamine-3 (5-HT3) RA… 
2018
2018
Compatibility and Stability of VARUBI (Rolapitant) Injectable Emulsion Admixed with Intravenous Granisetron Hydrochloride.
Prophylaxis or therapy with a combination of a neurokinin 1 (NK-1) receptor antagonist (RA), a 5-hydroxytryptamine- 3 (5-HT3) RA… 
Review
2017
Review
2017
Recent developments in the clinical pharmacology of rolapitant: subanalyses in specific populations
Knowledge of the involvement of the neurokinin substance P in emesis has led to the development of the neurokinin-1 receptor… 
Review
2016
Review
2016
Rolapitant hydrochloride: prophylactic treatment for chemotherapy-induced nausea and vomiting.
  • R. Navari
  • Drugs of Today
  • 2016
  • Corpus ID: 4836599
Chemotherapy-induced nausea and vomiting (CINV) is a significant clinical issue which affects patients' quality of life as well… 
2016
2016
Prophylaxe bei hochemetogener Chemotherapie
Chemotherapiebedingte Übelkeit und Erbrechen (CINV) gefährden den Erfolg onkologischer Therapien. Rolapitant ist ein neuartiger… 
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