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rolapitant hydrochloride
Known as:
Rolapitant Monohydrochloride Monohydrate
, 1,7-Diazaspiro(4.5)decan-2-one, 8-(((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-, Monohydrochloride, Monohydrate, (5S,8S)-
, Rolapitant HCl
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The hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with…
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National Institutes of Health
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SCH 619734
Varubi
rolapitant
rolapitant 90 MG Oral Tablet [Varubi]
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Absorption, metabolism, and excretion of the antiemetic rolapitant, a selective neurokinin-1 receptor antagonist, in healthy male subjects
Zhi-yi Zhang
,
Jing Wang
,
V. Kansra
,
Xiaodong Wang
Investigational new drugs
2018
Corpus ID: 51706858
SummaryRolapitant is a neurokinin-1 receptor antagonist that is approved in combination with other antiemetic agents in adults…
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2018
2018
Compatibility and Stability of VARUBI (Rolapitant) Injectable Emulsion Admixed with Intravenous Palonosetron Hydrochloride Injection and Dexamethasone Sodium Phosphate Injection.
George Wu
,
D. Powers
,
S. Yeung
,
Frank Chen
International journal of pharmaceutical…
2018
Corpus ID: 4042028
Prophylaxis or therapy with a combination of a neurokinin 1 (NK-1) receptor antagonist (RA), a 5-hydroxytryptamine-3 (5-HT3) RA…
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2018
2018
Compatibility and Stability of VARUBI (Rolapitant) Injectable Emulsion Admixed with Intravenous Granisetron Hydrochloride.
George Wu
,
D. Powers
,
S. Yeung
,
Frank Chen
,
K. Neelon
International journal of pharmaceutical…
2018
Corpus ID: 4022125
Prophylaxis or therapy with a combination of a neurokinin 1 (NK-1) receptor antagonist (RA), a 5-hydroxytryptamine- 3 (5-HT3) RA…
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Review
2017
Review
2017
Recent developments in the clinical pharmacology of rolapitant: subanalyses in specific populations
B. Rapoport
,
M. Aapro
,
+4 authors
L. Schwartzberg
Drug Design, Development and Therapy
2017
Corpus ID: 7817476
Knowledge of the involvement of the neurokinin substance P in emesis has led to the development of the neurokinin-1 receptor…
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Review
2016
Review
2016
Rolapitant hydrochloride: prophylactic treatment for chemotherapy-induced nausea and vomiting.
R. Navari
Drugs of Today
2016
Corpus ID: 4836599
Chemotherapy-induced nausea and vomiting (CINV) is a significant clinical issue which affects patients' quality of life as well…
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2016
2016
Prophylaxe bei hochemetogener Chemotherapie
K. Kieseritzky
2016
Corpus ID: 75750088
Chemotherapiebedingte Übelkeit und Erbrechen (CINV) gefährden den Erfolg onkologischer Therapien. Rolapitant ist ein neuartiger…
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