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rogletimide

Known as: 3-PYG, 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione, Pyridoglutethimide 
An orally active aminoglutethimide derivative with potential antineoplastic activity. Rogletimide reversibly inhibits the activity of aromatase, a… 
National Institutes of Health

Papers overview

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Review
1998
Review
1998
Epidemiological and experimental evidence strongly supports a role for estrogens in the development and growth of breast tumors… 
Highly Cited
1996
Highly Cited
1996
Highly Cited
1992
Highly Cited
1992
The influence of the prototype aromatase inhibitor Aminoglutethimide (AG) and its analogue Rogletimide (RG) on peripheral… 
1991
1991
Review
1991
Review
1991
  • R. Santen
  • The Journal of Steroid Biochemistry and Molecular…
  • 1991
  • Corpus ID: 12629201
1991
1991
The aromatase inhibitor, 'pyridoglutethimide' (PyG), has been shown previously to suppress serum oestrogen levels in… 
1990
1990
Inhibitors of the cytochrome P450 enzyme aromatase, which is involved in the biosynthesis of estrogens from androgens, are of… 
Review
1990
Review
1990
  • M. Dowsett
  • The Journal of Steroid Biochemistry and Molecular…
  • 1990
  • Corpus ID: 10515012
1990
1990
The inhibitory effects of pyridoglutethimide (3-ethyl-3-(4-pyridyl)piperidine-2,6-dione), an analogue of aminoglutethimide, on… 
1987
1987
3-Ethyl-3-(4-pyridyl)piperidine-2,6-dione (1) is a strong competitive inhibitor of human placental aromatase (Ki = 1.1 microM…