rogletimide

Known as: 3-PYG, 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione, Pyridoglutethimide 
An orally active aminoglutethimide derivative with potential antineoplastic activity. Rogletimide reversibly inhibits the activity of aromatase, a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2003
02419862003

Papers overview

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2004
2004
Kromasil CHI-DMB chiral stationary phase (CSP) is used to resolve some piperidine-2, 6-diones under normal mobile phase mode… (More)
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1992
1992
The influence of the prototype aromatase inhibitor Aminoglutethimide (AG) and its analogue Rogletimide (RG) on peripheral… (More)
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1991
1991
The aromatase inhibitor, 'pyridoglutethimide' (PyG), has been shown previously to suppress serum oestrogen levels in… (More)
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1991
1991
The aromatase inhibitor, 'pyridoglutethimide' (PyG), has been shown previously to suppress serum oestrogen levels in… (More)
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1991
1991
The pyridylglutarimide 3-ethyl-3-(4-pyridyl)-piperidine-2,6-dione (PyG) is a novel inhibitor of aromatase that was shown to cause… (More)
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Review
1991
Review
1991
The biological importance of aromatase rests in the concept that this is the rate-limiting enzyme involved in estrogen… (More)
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1991
1991
The antitumor effects of pyridoglutethimide (PG; 3-ethyl-3-(4-pyridyl) piperidine -2, 6-dione), a new analogue of… (More)
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1990
1990
The inhibitory effects of pyridoglutethimide (3-ethyl-3-(4-pyridyl)piperidine-2,6-dione), an analogue of aminoglutethimide, on… (More)
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1987
1987
3-Ethyl-3-(4-pyridyl)piperidine-2,6-dione (1) is a strong competitive inhibitor of human placental aromatase (Ki = 1.1 microM… (More)
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