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rizatriptan

Known as: rizatriptan [Chemical/Ingredient], Rizatriptán, N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine 
National Institutes of Health

Related topics

Related topics

13 relations
Angina Pectoris, VariantCerebral Arterial Vasoconstriction [PE]Drug AllergyRizatriptan Sulfate

Narrower (4)

MK 0462Rizatriptan benzoaterizatriptan 10 MG Disintegrating Oral Tabletrizatriptan 10 MG Oral Tablet

Broader (3)

Serotonin AgonistsTriazolesTryptamines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Triptans in the Acute Treatment of Migraine: A Systematic Review and Network Meta‐Analysis
Although triptans are widely used in the acute management of migraine, there is uncertainty around the comparative efficacy of… 
Review
2015
Review
2015
The Acute Treatment of Migraine in Adults: The American Headache Society Evidence Assessment of Migraine Pharmacotherapies
The study aims to provide an updated assessment of the evidence for individual pharmacological therapies for acute migraine… 
Highly Cited
2009
Highly Cited
2009
Elevated Saliva Calcitonin Gene‐Related Peptide Levels During Acute Migraine Predict Therapeutic Response to Rizatriptan
Objectives.— (1) To measure calcitonin gene‐related peptide (CGRP) levels in the saliva of individuals with migraine during the… 
Highly Cited
2008
Highly Cited
2008
Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine
Objective: To determine an effective and tolerable dose of a novel oral calcitonin gene-related peptide (CGRP) receptor… 
Review
2003
Review
2003
Migraine Headache Recurrence: Relationship to Clinical, Pharmacological, and Pharmacokinetic Properties of Triptans
Background and Objectives.—Triptan use is associated with headache recurrence, and this has been cited as an important reason for… 
Review
2002
Review
2002
Triptans (Serotonin, 5-HT1B/1D Agonists) in Migraine: Detailed Results and Methods of A Meta-Analysis of 53 Trials
The triptans, selective serotonin 5-HT1B/1D agonists, are very effective acute migraine drugs. Soon, seven different triptans… 
Review
2002
Review
2002
Pharmacological treatments for acute migraine: quantitative systematic review
Highly Cited
2001
Highly Cited
2001
Oral triptans (serotonin 5-HT1B/1D agonists) in acute migraine treatment: a meta-analysis of 53 trials
Highly Cited
1998
Highly Cited
1998
Oral Rizatriptan Versus Oral Sumatriptan: A Direct Comparative Study in the Acute Treatment of Migraine
Rizatriptan is a potent, oral, 5‐HT1B/1D agonist with more rapid absorption and higher bioavailability than oral sumatriptan. It… 
Highly Cited
1996
Highly Cited
1996
Rizatriptan vs sumatriptan in the acute treatment of migraine. A placebo-controlled, dose-ranging study. Dutch/US Rizatriptan Study Group.
BACKGROUND Rizatriptan (MK-462) is a new 5-hydroxytryptamine1D (serotonin1D; 5-HT1D) receptor agonist for the acute treatment of… 
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