ripoptosome

A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3… (More)

Topic mentions per year

Topic mentions per year

2012-2018
024620122018

Papers overview

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2017
2017
Constitutively active NFκB promotes survival of many cancers, especially T-cell lymphomas and leukemias by upregulating… (More)
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2015
2015
We recently described the induction of noncanonical IL-1β processing via caspase-8 recruited to ripoptosome signaling platforms… (More)
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2015
2015
ZFP36 is an mRNA binding protein that exerts anti-tumor activity in glioblastoma by triggering cell death, associated to an… (More)
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2014
2014
Apoptosis resistance contributes to poor outcome in pediatric acute lymphoblastic leukemia (ALL). Here, we identify a novel… (More)
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2014
2014
L929 fibroblastoma cells (L929-A) and L929 fibrosarcoma cells (L929-N) are different cell lines that are commonly used to study… (More)
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2013
2013
In the lymph node (LN) environment, chronic lymphocytic leukemia (CLL) cells display increased NF-κB activity compared with… (More)
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Highly Cited
2013
Highly Cited
2013
Ligation of tumor necrosis factor receptor 1 (TNFR1) can cause cell death by caspase 8 or receptor-interacting protein kinase 1… (More)
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2013
2013
2013
Apoptosis and necroptosis are dependent on the formation/activation of distinct multi-protein complexes; these include the Death… (More)
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Highly Cited
2012
Highly Cited
2012
Interleukin-1β (IL-1β) is a potent inflammatory cytokine that is usually cleaved and activated by inflammasome-associated caspase… (More)
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