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ripoptosome

A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Cytoplasmic matrix
necrosome

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Ripoptosome Analysis by Caspase-8 Coimmunoprecipitation.
The biochemical signaling of cell death pathways is executed at a number of different intracellular and/or membrane-bound high… 
2016
2016
Abstract 3020: Targeting both canonical and non-canonical NF-kB pathways by the IAP antagonist birinapant potentiates bortezomib anti-myeloma activity
Inhibitor of apoptosis proteins (IAPs e.g., XIAP, cIAP1, cIAP2) inhibit apoptosis through diverse mechanisms. Recent attention… 
2016
2016
Obituary: Professor Martin Leverkus: 1965-2016.
2015
2015
Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIPL degradation, Ripoptosome formation and autophagy-mediated apoptosis
Drug resistance is a major hurdle in anticancer chemotherapy. Combined therapy using drugs with distinct mechanisms of function… 
2015
2015
A dual tool. The role of the ripoptosome in phagocytic cell activation and differentiation
El termino ripoptosoma hace referencia a la plataforma molecular que contiene, entre otras, dos proteinas implicadas en muerte… 
2014
2014
SMAC-armed vaccinia virus induces both apoptosis and necroptosis and synergizes the efficiency of vinblastine in HCC
Hepatocellular carcinoma (HCC) has particularly high incidence rate in Asia and its resistance to the chemotherapeutic drugs and… 
Review
2014
Review
2014
Characterization of the ripoptosome and its components: implications for anti-inflammatory and cancer therapy.
2013
2013
Isolation, characterisation and reconstitution of cell death signalling complexes.
2013
2013
Abstract 2944: AT-IAP, a dual cIAP1 and XIAP antagonist with oral antitumor activity in melanoma models.
Melanoma is a highly aggressive malignancy with an exceptional ability to develop resistance and no curative therapy is available… 
2013
2013
Altération du ripoptosome dans la leucémie aiguë myéloïde
The receptor-interacting protein kinase 1 (RIP1) and 3 (RIP3) are key signaling molecules in the regulation of apoptotic cell… 
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