Characterization of the ripoptosome and its components: implications for anti-inflammatory and cancer therapy.

@article{Schilling2014CharacterizationOT,
  title={Characterization of the ripoptosome and its components: implications for anti-inflammatory and cancer therapy.},
  author={Ramon Schilling and Peter Geserick and Martin Leverkus},
  journal={Methods in enzymology},
  year={2014},
  volume={545},
  pages={
          83-102
        }
}
  • Ramon Schilling, Peter Geserick, Martin Leverkus
  • Published in Methods in enzymology 2014
  • Chemistry, Biology, Medicine
  • Most intracellular signaling cascades rely on the formation of multiprotein signaling complexes assembled in large protein signaling platforms. Especially in cell death signaling, there is a large variety of these complexes, including the apoptosome, the necrosome, or the death-inducing signaling complex (DISC), to name only a few. During the last years, a number of cellular conditions were identified that lead to the formation of another signaling platform, the so-called ripoptosome. Diverse… CONTINUE READING

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