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rilmakalim

Known as: 2-Pyrrolidinone, 1-(3,4-dihydro-3-hydroxy-2,2-dimethyl-6-(phenylsulfonyl)-2H-1-benzopyran-4-yl)-, (3S-trans)-, 3-hydroxy-2,3-dimethyl-4-(2-oxo-1-pyrrolidinyl)-6-phenylsulfonylchroman hemihydrate, rimalkalim 
National Institutes of Health

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6 relations

Broader (5)

Anti-Arrhythmia AgentsBronchodilator AgentsChromansMuscle Relaxants, Central

Narrower (1)

HOE 234

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Hypotonic stress enhances slope conductivity of ATP-sensitive K+ channels activated pharmacologically.
2006
2006
Selective inhibition of pinacidil effects by estrogen in guinea pig heart.
2004
2004
Effects of a Novel Cardioselective ATP-Sensitive Potassium Channel Antagonist, 1-[[5-[2-(5-Chloro-o-anisamido)ethyl]-β-methoxyethoxyphenyl]sulfonyl]-3-methylthiourea, Sodium Salt (HMR 1402), on…
In the present study, a novel sulfonylthiourea, 1-[[5-[2-(5-chloro-o-anisamido)ethyl]-β-methoxyethoxyphenyl]sulfonyl]-3… 
2004
2004
Effect of two amino acids in TM17 of Sulfonylurea receptor SUR1 on the binding of ATP-sensitive K+ channel modulators.
The sulfonylurea receptor (SUR) is the important regulatory subunit of ATP-sensitive K+ channels. It is an ATP-binding cassette… 
2004
2004
Hypotonic stress increases efficacy of rilmakalim, but not pinacidil, to activate ATP-sensitive K(+) current in guinea pig ventricular myocytes.
The aim of this study was to investigate the influence of hypotonic challenge on the effects of potassium channel openers (PCO… 
2003
2003
Synthesis and structure of novel 2,3, 5,6-tetrahydro-1H-imidazo[2,1-b][1,3,5]benzotriazepines with vasocontractile activity in rabbit aortic rings.
2003
2003
Selective Block of Sarcolemmal IKATP in Human Cardiomyocytes Using HMR 1098
AbstractPurpose: Activation of the myocardial, ATP-dependent potassium current (IKATP) during ischemia causes shortening of the… 
2001
2001
Cardioselective K(ATP) channel blockers derived from a new series of m-anisamidoethylbenzenesulfonylthioureas.
Sulfonylthioureas exhibiting cardioselective blockade of ATP-sensitive potassium channels (K(ATP) channels) were discovered by… 
1995
1995
Hypoxia-induced activation of KATP channels limits energy depletion in the guinea pig heart.
The functional role of ATP-dependent potassium (KATP) in hypoxic cardiac failure was investigated in isolated guinea pig hearts… 
1995
1995
Adenosine triphosphate-dependent K currents activated by metabolic inhibition in rat ventricular myocytes differ from those elicited by the channel opener rilmakalim
Adenosine triphosphate (ATP) dependent potassium channels (KATP channels) in heart ventricular muscle cells can be activated by… 
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