ribosomal protein L5, human

Known as: 60S Ribosomal Protein L5, RPL5 protein, human, RPL5 
60S ribosomal protein L5 (297 aa, ~34 kDa) is encoded by the human RPL5 gene. This protein plays a role in both ribosome formation and RNA binding.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2018
0246820022018

Papers overview

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2015
2015
Over the past decade, a number of ribosomal proteins (RPs) have been found to have a role in activating the tumor suppressor p53… (More)
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2014
2014
Oncogene MYC is highly expressed in many human cancers and functions as a global regulator of ribosome biogenesis. Previously, we… (More)
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Highly Cited
2013
Highly Cited
2013
Several proto-oncogenes and tumor suppressors regulate the production of ribosomes. Ribosome biogenesis is a major consumer of… (More)
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Highly Cited
2013
Highly Cited
2013
Recently, we demonstrated that RPL5 and RPL11 act in a mutually dependent manner to inhibit Hdm2 and stabilize p53 following… (More)
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2013
2013
Humans have evolved elaborate mechanisms to activate p53 in response to insults that lead to cancer, including the binding and… (More)
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2012
2012
Members of the β-karyopherin family mediate nuclear import of ribosomal proteins and export of ribosomal subunits, both required… (More)
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2011
2011
A number of external and internal insults disrupt nucleolar structure, and the resulting nucleolar stress stabilizes and… (More)
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2010
2010
BACKGROUND Diamond-Blackfan anemia is a rare, pure red blood cell aplasia of childhood due to an intrinsic defect in… (More)
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2009
2009
Diamond-Blackfan anemia (DBA) is a congenital red blood cell aplasia that is usually diagnosed during early infancy. Apart from… (More)
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2004
2004
Gene transfer from the mitochondrion to the nucleus, a process of outstanding importance to the evolution of the eukaryotic cell… (More)
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