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The ribosomal protein S6K (S6 kinase) represents an extensively studied effector of the TORC1 [TOR (target of rapamycin) complex… Expand Ribosomal proteins are ubiquitous, abundant, and RNA binding: prime candidates for recruitment to extraribosomal functions… Expand MicroRNAs (miRNAs) are small RNAs that function as posttranscriptional regulators of gene expression. miRNAs affect a variety of… Expand Converging signals from the mammalian target of rapamycin (mTOR) and phosphoinositide 3-kinase (PI3K) pathways are well… Expand Recent studies are beginning to disclose a signaling network involved in regulating cell size. Although many links and effectors… Expand The HDM2 protein plays an important role in regulating the stability and function of the p53 tumor suppressor protein. In this… Expand ABSTRACT The gene encoding p53 mediates a major tumor suppression pathway that is frequently altered in human cancers. p53… Expand The discovery of DNA-binding motifs in ribosomal proteins has led to the conjecture that the transition of the ribosome from an… Expand In rat hepatocytes, autophagy is known to be inhibited by amino acids. Insulin and cell swelling promote inhibition by amino… Expand Three of the four yeast ubiquitin genes encode hybrid proteins which are cleaved to yield ubiquitin and previously unidentified… Expand