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ribocil

 
National Institutes of Health

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Pyrimidines

Papers overview

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2018
2018
Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry.
Recent advances in understanding the relevance of noncoding RNA (ncRNA) to disease have increased interest in drugging ncRNA with… Expand
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2018
2018
Validation and Development of an Escherichia coli Riboflavin Pathway Phenotypic Screen Hit as a Small-Molecule Ligand of the Flavin Mononucleotide Riboswitch.
A riboflavin biosynthesis pathway-specific phenotypic screen using a library of compounds, all with unspecified antibiotic… Expand
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2017
2017
Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.
Riboswitches are bacterial-specific, broadly conserved, non-coding RNA structural elements that control gene expression of… Expand
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2016
2016
Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of the E. coli FMN riboswitch
Bacterial riboswitches are non-coding RNA structural elements that direct gene expression in numerous metabolic pathways. The key… Expand
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Highly Cited
2015
Highly Cited
2015
Selective small-molecule inhibition of an RNA structural element
Riboswitches are non-coding RNA structures located in messenger RNAs that bind endogenous ligands, such as a specific metabolite… Expand
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2015
2015
Dissecting How Mtb Makes Its Wall, Buffering Endosomal pH, and Discovery of Ribocil.
Each month, Chemistry & Biology Select highlights a selection of research reports from the recent literature. These highlights… Expand
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2015
2015
Riboswitches: A bacterial antivitamin.
Antimicrobial strategies frequently target bacterial pathways that follow distinct routes from those in the human host or that… Expand
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2015
2015
A bacterial antivitamin
  • 2015
    • Corpus ID: 31542958
Antimicrobial strategies frequently target bacterial pathways that follow distinct routes from those in the human host or that… Expand
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