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rhodostomin

National Institutes of Health

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Broader (2)

PeptidesPlatelet Aggregation Inhibitors

Papers overview

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2017
2017
Effects of the RGD loop and C-terminus of rhodostomin on regulating integrin αIIbβ3 recognition
Rhodostomin (Rho) is a medium disintegrin containing a 48PRGDMP motif. We here showed that Rho proteins with P48A, M52W, and P53N… 
2009
2009
Effect of D to E mutation of the RGD motif in rhodostomin on its activity, structure, and dynamics: Importance of the interactions between the D residue and integrin
Rhodostomin (Rho) is a snake venom protein containing an RGD motif that specifically inhibits the integrin‐binding function. Rho… 
2005
2005
Preparation of amino‐acid‐type selective isotope labeling of protein expressed in Pichia pastoris
We report the culture conditions for successful amino‐acid‐type selective (AATS) isotope labeling of protein expressed in Pichia… 
2005
2005
Rhodostomin inhibits thrombin-enhanced adhesion of ROS 17/2.8 cells through the blockade of alphavbeta3 integrin.
Osteosarcoma is a very malignant bone tumor which has a high metastatic potential and usually lead to poor prognosis. The… 
2004
2004
Rhodostomin, a Disintegrin, Inhibits Adhesion of Neutrophils to Fibrinogen and Attenuates Superoxide Production
Disintegrins are a group of Arg (or Lys)-Gly-Asp-containing snake venom proteins which inhibit platelet aggregation via the… 
2003
2003
Disintegrin causes proteolysis of beta-catenin and apoptosis of endothelial cells. Involvement of cell-cell and cell-ECM interactions in regulating cell viability.
Disintegrins, the snake venom-derived arginine-glycine-aspartic acid-containing peptides, have been demonstrated to inhibit… 
2001
2001
Viper Venom Components Affecting Angiogenesis
Angiogenesis is a complex process consisting of the proliferation, migration and differentiation of endothelial cells, and it is… 
1999
1999
Recombinant rhodostomin substrates induce transformation and active calcium oscillation in human platelets.
Platelet activation has been a focus of numerous studies in normal and abnormal states. Morphological changes and calcium signals… 
1995
1995
Crotavirin, a potent platelet aggregation inhibitor purified from the venom of the snake Crotalus viridis.
1994
1994
Analysis of Human Platelet Glycoprotein llb-llla by Fluorescein Isothiocyanate-Conjugated Disintegrins with Flow Cytometry
Summary Disintegrins are a group of snake venom peptides which inhibit human platelet aggregation by acting as glycoprotein Ilb… 
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