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retinylamine

Known as: Retinamine 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Diterpenes

Narrower (2)

cis-retinylaminetrans-retinylamine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Retinylamine Benefits Early Diabetic Retinopathy in Mice*
Background: The development of diabetic retinopathy (DR) is incompletely understood. Administered retinylamine is stored in the… 
Highly Cited
2009
Highly Cited
2009
Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.
Inactivating mutations in the retinoid isomerase (RPE65) or lecithin:retinol acyltransferase (LRAT) genes cause Leber congenital… 
2009
2009
Quantitative mapping of ion channel regulation by visual cycle activity in rodent photoreceptors in vivo.
PURPOSE To test the hypothesis that the extent of outer retina uptake of manganese, measured noninvasively with manganese… 
Highly Cited
2008
Highly Cited
2008
Retinopathy in Mice Induced by Disrupted All-trans-retinal Clearance*
The visual (retinoid) cycle is a fundamental metabolic process in vertebrate retina responsible for production of 11-cis-retinal… 
Highly Cited
2008
Highly Cited
2008
Metabolic Basis of Visual Cycle Inhibition by Retinoid and Nonretinoid Compounds in the Vertebrate Retina*
In vertebrate retinal photoreceptors, the absorption of light by rhodopsin leads to photoisomerization of 11-cis-retinal to its… 
Highly Cited
2007
Highly Cited
2007
Redundant and unique roles of retinol dehydrogenases in the mouse retina
Highly abundant short-chain alcohol dehydrogenases (RDHs) in the retina were assumed to be involved in the recycling of 11-cis… 
Highly Cited
2006
Highly Cited
2006
Effects of Potent Inhibitors of the Retinoid Cycle on Visual Function and Photoreceptor Protection from Light Damage in Mice
Regeneration of the chromophore 11-cis-retinal is essential for the generation of light-sensitive visual pigments in the… 
Highly Cited
2005
Highly Cited
2005
Lecithin:Retinol Acyltransferase Is Responsible for Amidation of Retinylamine, a Potent Inhibitor of the Retinoid Cycle*
Lecithin:retinol acyltransferase (LRAT) catalyzes the transfer of an acyl group from the sn-1 position of phosphatidylcholine to… 
Highly Cited
2005
Highly Cited
2005
Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle.
In vertebrate retinal photoreceptors, photoisomerization of opsin-bound visual chromophore 11-cis-retinal to all-trans-retinal… 
1997
1997
Synthesis and characterization of a novel retinylamine analog inhibitor of constitutively active rhodopsin mutants found in patients with autosomal dominant retinitis pigmentosa.
Two different mutations of the active-site Lys-296 in rhodopsin, K296E and K296M, have been found to cause autosomal dominant… 
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