B. Snider

Publications502
h-index46
Citations9,467
Highly Influential Citations29
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In vitro hepatotoxicity of the cyanobacterial alkaloid cylindrospermopsin and related synthetic analogues.
TLDR
The sulfate group was found not to play a role in CY activity or in its uptake into cells, since there was no significant difference in biological activity in vitro or in cells between natural CY and CY-DIOL.
Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c
TLDR
This strategy identified a previously unknown, Mycobacterium tuberculosis-specific lipid, 1-tuberculosinyladenosine, which is produced by the Rv3378c enzyme, and establishes its role as a tuberculo-prenyl transferase and suggests a revised biosynthetic pathway for the sequential action of Rv 3377c-Rv 3378c.
Synthesis of 2,3-dihydro-3-hydroxy-2-hydroxylalkylbenzofurans from epoxy aldehydes. One-step syntheses of brosimacutin G, vaginidiol, vaginol, smyrindiol, xanthoarnol, and Avicenol A. Biomimetic…
We have developed two practical one-step syntheses of 2,3-dihydro-3-hydroxy-2-hydroxyalkylbenzofurans from readily available optically pure alpha,beta-epoxy aldehydes. Electron-deficient resorcinols…
Syntheses of (-)-TAN-2483A, (-)-Massarilactone B, and the Fusidilactone B Ring System. Revision of the Structures of and Syntheses of (.+-.)-Waol A (FD-211) and (.+-.)-Waol B (FD-212).
Total Synthesis of (+/-)-Leporin A.
An efficient synthesis of (+/-)-leporin A (1) has been developed using a tandem Knoevenagel condensation-inverse electron demand intramolecular hetero Diels-Alder reaction to construct the key…
An Improved Procedure for the Conversion of Alkenes and Glycals to 1,2-Diazides Using Mn(OAc)3·2H2O in Acetonitrile Containing Trifluoroacetic Acid
Abstract Alkenes and Glycals react with Mn(OAc3)·2H2O and NaN3 in 9:1 acetonitrile-trifluoroacetic acid to give 1,2-diazides in >80% yield. Allylic azides are formed by slow addition of NaN3 to a…
In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection.
TLDR
It is shown that the recently identified compound, 1-tuberculosinyladenosine (1-TbAd), accumulates to comprise >1% of all Mycobacterium tuberculosis lipid.
Synthesis of (+/-)-eusynstyelamide A.
The synthesis of (+/-)-eusynstyelamide A has been accomplished in six steps in 13% overall yield from 6-bromoindole, methyl glycidate, and Boc-protected agmatine. If oxygen is carefully excluded from…
Oxidative and dehydrative cyclizations of nitroacetate esters with Mn(OAc)3
Abstract Reaction of α-unsubstituted nitroacetates with Mn(OAc)3 gives mixtures of isoxazolines, formed by dehydration to a nitrile oxide that undergoes cycloaddition, and isoxazoline oxides or…
Synthesis of (+)-sch 642305 by a biomimetic transannular Michael reaction.
TLDR
The synthesis of (+)-Sch 642305 (1) has been completed in 17 steps in 1.6% overall yield, with high overall yield of cyclohexenone 23 stereospecifically.
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