ret-PTC-3 oncoprotein, human
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TrkAIII expression in neuroblastoma (NB) associates with advanced stage disease, worse prognosis, post therapeutic relapse, and… Expand The epidermal growth factor receptor (EGFR) is upregulated in numerous human cancers. Inhibition of EGFR signaling induces… Expand The oncoprotein EZH2, as a histone H3K27 methyltransferase, is frequently overexpressed in various cancer types. However, the… Expand Mucin 1 (MUC1) is a heterodimeric protein formed by two subunits that is aberrantly overexpressed in human breast cancer and… Expand MicroRNAs (miRNAs) play critical roles in tumorigenesis by modulating the expression of target gene mRNAs. However, their role in… Expand Background: Classical zinc finger proteins are extremely abundant and interact with DNA using a well defined recognition code… Expand BACKGROUND & AIMS
RNA interference (RNAi) is a powerful tool to silence gene expression. The adenoviral vector expressing small… Expand The HDMX protein is closely related to HDM2 with which it shares different structural domains, particularly the p53 binding… Expand The Hdm2 oncoprotein inhibits p53 functions by two means: (i) it blocks p53's transactivation activity and (ii) it targets p53… Expand The 79-amino-acid (79-aa) open reading frame (UL111a) gene within morphological transforming region II (mtrII) of human… Expand