response to paracetamol

Known as: response to acetaminophen 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… (More)

Topic mentions per year

Topic mentions per year

1980-2018
012319802018

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2016
2016
Primary human hepatocytes (hHEP), human HepaRG and HepG2 cell lines are the most used human liver-based in vitro models for… (More)
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2016
2016
Acetaminophen is a commonly used analgesic that can cause severe hepatotoxicity in overdose. Despite old age and frailty being… (More)
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2015
2015
Acute liver failure is a rare but catastrophic condition which can progress rapidly to multi-organ failure. Studies investigating… (More)
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2014
2014
Paracetamol (acetaminophen) is one of the most commonly used drugs for the treatment of pain and fever in children, both at home… (More)
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2012
2012
Primary hepatocytes have been used in drug development for the evaluation of hepatotoxicity of candidate compounds. However, the… (More)
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2005
2005
Drug-metabolizing enzymes and membrane transporters are responsible for the detoxication and elimination of xenobiotics from the… (More)
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2003
2003
OBJECTIVE The hepatic toxic response to acetaminophen (APAP) is characterized by centrilobular (CL) necrosis preceded by hepatic… (More)
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2003
2003
Hepatocyte proliferation represents an important part of tissue repair. In these studies, TNF receptor 1 (TNFR1) knockout mice… (More)
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1988
1988
Over 60% of the analgesic/antipyretic drug acetaminophen is eliminated by glucuronidation, which competes with a toxifying… (More)
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1987
1987
The effect of acetaminophen on fever in bacterial vs. viral infections was tested in 100 children ages 9 days to 17 years who… (More)
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