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Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis.
BACKGROUND & AIMS Patients with cirrhosis hospitalized for an acute decompensation (AD) and organ failure are at risk for imminent death and considered to have acute-on-chronic liver failure (ACLF).… Expand
Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis
Objectives To propose an improvement on the current classification of renal dysfunction in cirrhosis. Clinicians caring for patients with cirrhosis recognize that the development of renal dysfunction… Expand
Acute-on chronic liver failure.
Acute-on-chronic liver failure (ACLF) is an increasingly recognised entity encompassing an acute deterioration of liver function in patients with cirrhosis, which is usually associated with a… Expand
Bacterial infections in cirrhosis: a position statement based on the EASL Special Conference 2013.
Bacterial infections are very common and represent one of the most important reasons of progression of liver failure, development of liver-related complications, and mortality in patients with… Expand
Liver failure after partial hepatic resection: definition, pathophysiology, risk factors and treatment
- M. A. J. van den Broek, S. O. Olde Damink, +4 authors F. Saner
- Liver international : official journal of the…
- 1 July 2008
Liver failure is a dreaded and often fatal complication that sometimes follows a partial hepatic resection. This article reviews the definition, incidence, pathogenesis, risk factors, risk… Expand
Clinical Course of acute‐on‐chronic liver failure syndrome and effects on prognosis
Acute‐on‐chronic liver failure (ACLF) is characterized by acute decompensation (AD) of cirrhosis, organ failure(s), and high 28‐day mortality. We investigated whether assessments of patients at… Expand
Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute‐on‐chronic liver failure: The RELIEF trial
Acute‐on‐chronic liver failure (ACLF) is a frequent cause of death in cirrhosis. Albumin dialysis with the molecular adsorbent recirculating system (MARS) decreases retained substances and improves… Expand
A histologic scoring system for prognosis of patients with alcoholic hepatitis.
BACKGROUND & AIMS There is no histologic classification system to determine prognoses of patients with alcoholic hepatitis (AH). We identified histologic features associated with disease severity and… Expand
Interorgan ammonia and amino acid metabolism in metabolically stable patients with cirrhosis and a TIPSS
- Steven W. M. Olde Damink, R. Jalan, D. Redhead, P. Hayes, Nicolaas E. P. Deutz, Peter B. Soeters
- Biology, Medicine
- 1 November 2002
Ammonia is central to the pathogenesis of hepatic encephalopathy. This study was designed to determine the quantitative dynamics of ammonia metabolism in patients with cirrhosis and previous… Expand
Endotoxemia produces coma and brain swelling in bile duct ligated rats
This study explores the hypothesis that the inflammatory response induced by administration of lipopolysaccharide (LPS) exacerbates brain edema in cirrhotic rats; and if so whether this is associated… Expand