response to lapatinib

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… (More)

Topic mentions per year

Topic mentions per year

2006-2017
02420062017

Papers overview

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2017
2017
  • Nature
  • 2017
Cervical cancer remains one of the leading causes of cancer-related deaths worldwide. Here we report the extensive molecular… (More)
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2015
2015
BACKGROUND Lapatinib is a dual epidermal growth factor receptor (EGFR) and HER2 inhibitor. Overexpression of these receptors is… (More)
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2013
2013
OBJECTIVE Lapatinib, a dual HER2/EGFR tyrosine kinase inhibitor (TKI), associated to capecitabine represents the treatment of… (More)
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2013
2013
HER2 targeted therapies including trastuzumab and more recently lapatinib have significantly improved the prognosis for HER2… (More)
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2013
2013
STUDY OBJECTIVE To determine if development of acneiform rash is a predictor of objective response rate with lapatinib. DESIGN… (More)
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2012
2012
Lapatinib, a tyrosine kinase inhibitor of HER2 and EGFR and is approved, in combination with capecitabine, for the treatment of… (More)
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2010
2010
Lapatinib and capecitabine combination therapy is effective in trastuzumab-resistant human epidermal growth factor receptor 2… (More)
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2010
2010
For breast cancer patients, treatment decisions based on the molecular profile of the primary tumor have been used for many years… (More)
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2010
2010
We have read with great interest the article by Downey et al. on chromosome 17 polysomy without HER2 amplification and prediction… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Lapatinib (Tykerb, GW572016), a potent inhibitor of the catalytic activities of epidermal growth factor receptor (EGFR… (More)
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