representational difference analysis

Known as: RDA, rdas 
This PCR technique enables researchers to compare the DNA of normal and afflicted tissue to isolate the DNA regions gained or lost in disease… (More)
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
We have characterized comprehensive transcript and proteomic profiles of cell lines corresponding to normal breast (MCF10A… (More)
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2004
2004
In this chapter 1 describe the PCR-coupled subtractive hybridization technique of representational difference analysis of cDNA… (More)
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Highly Cited
2001
Highly Cited
2001
This paper examines how to obtain species biplots in unconstrained or constrained ordination without resorting to the Euclidean… (More)
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Highly Cited
1999
Highly Cited
1999
We present a new multivariate technique for testing the significance of individual terms in a multifactorial analysis-of-variance… (More)
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Highly Cited
1998
Highly Cited
1998
The identification of differential gene expressionbetween cells is a frequent goal in modern biological research. Here we… (More)
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Highly Cited
1998
Highly Cited
1998
To determine the human folate requirement on the basis of changes in biochemical pathways, we studied the effect of controlled… (More)
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Highly Cited
1997
Highly Cited
1997
Methylation of CpG sites in the genome, which is generally conserved during cell replication, is considered to play important… (More)
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Review
1995
Review
1995
Representational difference analysis (RDA) is an efficient method for finding the differences between complex genomes. The… (More)
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Highly Cited
1994
Highly Cited
1994
Detection of differentially regulated genes has been severely hampered by technical limitations. In an effort to overcome these… (More)
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Highly Cited
1993
Highly Cited
1993
The analysis of the differences between two complex genomes holds promise for the discovery of infectious agents and probes… (More)
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