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relaxation of vascular smooth muscle

Known as: vascular smooth muscle relaxation 
A process in which the extent of vascular smooth muscle contraction is reduced. Vascular smooth muscle relaxation is mediated via a decrease in the… Expand
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Vasodilation

Papers overview

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Highly Cited
2007
Highly Cited
2007
Thrombospondin-1 limits ischemic tissue survival by inhibiting nitric oxide-mediated vascular smooth muscle relaxation.
The nitric oxide (NO)/cGMP pathway, by relaxing vascular smooth muscle cells, is a major physiologic regulator of tissue… Expand
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Highly Cited
2003
Highly Cited
2003
Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure
Nitric oxide (NO) inhibits vascular contraction by activating cGMP-dependent protein kinase I-α (PKGI-α), which causes… Expand
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Highly Cited
2001
Highly Cited
2001
Nitric oxide contributes to vascular smooth muscle relaxation in contracting fast-twitch muscles.
During skeletal muscle contraction, NO derived from neuronal nitric oxide synthase (nNOS) in skeletal muscle fibers or from… Expand
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Highly Cited
1998
Highly Cited
1998
Relaxin activates the L-arginine-nitric oxide pathway in vascular smooth muscle cells in culture.
The peptide hormone relaxin (RLX) has been shown to elicit a powerful vasodilatory response in several target organs. This… Expand
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Review
1995
Review
1995
Endothelium-dependent hyperpolarization: a role in the control of vascular tone.
Endothelial-dependent relaxation of vascular smooth muscle cells evoked by a number of agonists, including cholinomimetics and… Expand
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Review
1994
Review
1994
Sumatriptan. A reappraisal of its pharmacology and therapeutic efficacy in the acute treatment of migraine and cluster headache.
Sumatriptan is a potent and selective agonist at a vascular serotonin1 (5-hydroxytryptamine1; 5-HT1) receptor subtype (similar to… Expand
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Review
1988
Review
1988
Biochemical mechanisms underlying vascular smooth muscle relaxation: the guanylate cyclase-cyclic GMP system.
Several classes of vasodilators have been demonstrated to elicit their affects by activating guanylate cyclase and elevating… Expand
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Highly Cited
1986
Highly Cited
1986
Effect of hypercholesterolemia on vascular reactivity in the rabbit. I. Endothelium-dependent and endothelium-independent contractions and relaxations in isolated arteries of control and…
We studied the effects of hypercholesterolemia on vascular responsiveness in different arteries isolated from rabbits: control… Expand
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Highly Cited
1982
Highly Cited
1982
Calcium- and endothelial-mediated vascular smooth muscle relaxation in rabbit aorta
The role of calcium in the relaxations evoked by methacholine and A23187 in intact rabbit aortic rings was investigated… Expand
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Highly Cited
1981
Highly Cited
1981
Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.
 
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