Skip to search formSkip to main contentSkip to account menu

refractory cancer

Known as: clinical resistance, resistant cancer, cancer refractory 
Cancer that does not respond to treatment. The cancer may be resistant at the beginning of treatment, or it may become resistant during treatment.
National Institutes of Health

Related topics

Related topics

2 relations
Neoplastic Cellcancer cell

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Down-regulation of HSP27 sensitizes TRAIL-resistant tumor cell to TRAIL-induced apoptosis.
Highly Cited
2009
Highly Cited
2009
Dose-Ranging Study of Metronomic Oral Vinorelbine in Patients with Advanced Refractory Cancer
Aim: To determine the safe dose range and pharmacokinetics of metronomic oral vinorelbine and obtain preliminary data on… 
Highly Cited
2004
Highly Cited
2004
Platinum(IV) complex with adamantylamine as nonleaving amine group: synthesis, characterization, and in vitro antitumor activity against a panel of cisplatin-resistant cancer cell lines.
Procedure of the synthesis is described for new platinum(IV) drug LA-12 [(OC-6-43)-bis(acetato)(1-adamantylamine… 
Review
2003
Review
2003
Targeting cancer cells by exploiting their resistance.
Review
1997
Review
1997
Comparison of estrogen receptor DNA binding in untreated and acquired antiestrogen-resistant human breast tumors.
Preliminary studies have suggested that measuring the ability of immunoreactive 67-kDa estrogen receptor (ER) to bind DNA and… 
Highly Cited
1986
Highly Cited
1986
Administration of intraspinal morphine sulfate for the treatment of intractable cancer pain.
A total of 24 patients with intractable cancer pain were evaluated as candidates for spinal morphine therapy. Temporary trials… 
Highly Cited
1984
Highly Cited
1984
Improved control of bulky prostate carcinoma with sequential estrogen and radiation therapy.
Highly Cited
1981
Highly Cited
1981
High-dose combined-modality therapy and autologous bone marrow transplantation in resistant cancer.
1979
1979
Treatment of metastatic endocrine-unresponsive carcinoma of the prostate gland with multiagent chemotherapy: indicators of response to therapy.
Eighty-eight patients with metastatic and hormonally unresponsive carcinoma of the prostate gland were treated with a multiagent… 
1962
1962
Correlations of the biochemical and clinical effects of 6-azauridine in patients with leukemia
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)