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refractory cancer
Known as:
clinical resistance
, resistant cancer
, cancer refractory
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Cancer that does not respond to treatment. The cancer may be resistant at the beginning of treatment, or it may become resistant during treatment.
National Institutes of Health
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Related topics
Related topics
2 relations
Neoplastic Cell
cancer cell
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Down-regulation of HSP27 sensitizes TRAIL-resistant tumor cell to TRAIL-induced apoptosis.
Hongqin Zhuang
,
Weiwei Jiang
,
+10 authors
Z. Hua
Lung Cancer
2010
Corpus ID: 34781807
Highly Cited
2009
Highly Cited
2009
Dose-Ranging Study of Metronomic Oral Vinorelbine in Patients with Advanced Refractory Cancer
E. Briasoulis
,
P. Pappas
,
+5 authors
N. Pavlidis
Clinical Cancer Research
2009
Corpus ID: 9578142
Aim: To determine the safe dose range and pharmacokinetics of metronomic oral vinorelbine and obtain preliminary data on…
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Highly Cited
2004
Highly Cited
2004
Platinum(IV) complex with adamantylamine as nonleaving amine group: synthesis, characterization, and in vitro antitumor activity against a panel of cisplatin-resistant cancer cell lines.
Frantisek Zák
,
J. Turánek
,
+10 authors
A. Kozubík
Journal of Medicinal Chemistry
2004
Corpus ID: 38536799
Procedure of the synthesis is described for new platinum(IV) drug LA-12 [(OC-6-43)-bis(acetato)(1-adamantylamine…
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Review
2003
Review
2003
Targeting cancer cells by exploiting their resistance.
M. Blagosklonny
Trends in Molecular Medicine
2003
Corpus ID: 31888588
Review
1997
Review
1997
Comparison of estrogen receptor DNA binding in untreated and acquired antiestrogen-resistant human breast tumors.
S. Johnston
,
B. Lu
,
+5 authors
C. Benz
Cancer Research
1997
Corpus ID: 23100085
Preliminary studies have suggested that measuring the ability of immunoreactive 67-kDa estrogen receptor (ER) to bind DNA and…
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Highly Cited
1986
Highly Cited
1986
Administration of intraspinal morphine sulfate for the treatment of intractable cancer pain.
A. Shetter
,
M. Hadley
,
E. Wilkinson
1986
Corpus ID: 53757490
A total of 24 patients with intractable cancer pain were evaluated as candidates for spinal morphine therapy. Temporary trials…
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Highly Cited
1984
Highly Cited
1984
Improved control of bulky prostate carcinoma with sequential estrogen and radiation therapy.
N. Green
,
H. Bodner
,
+7 authors
J. Jaffe
International Journal of Radiation Oncology…
1984
Corpus ID: 24623295
Highly Cited
1981
Highly Cited
1981
High-dose combined-modality therapy and autologous bone marrow transplantation in resistant cancer.
D. Douer
,
R. Champlin
,
+5 authors
R. Gale
American Journal of Medicine
1981
Corpus ID: 9146672
1979
1979
Treatment of metastatic endocrine-unresponsive carcinoma of the prostate gland with multiagent chemotherapy: indicators of response to therapy.
D. Paulson
,
W. Berry
,
E. Cox
,
A. Walker
,
J. Laszlo
Journal of the National Cancer Institute
1979
Corpus ID: 33087841
Eighty-eight patients with metastatic and hormonally unresponsive carcinoma of the prostate gland were treated with a multiagent…
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1962
1962
Correlations of the biochemical and clinical effects of 6-azauridine in patients with leukemia
H. Fallon
,
E. Frei
,
E. Freireich
1962
Corpus ID: 71329985
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