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refractory cancer

Known as: clinical resistance, resistant cancer, cancer refractory 
Cancer that does not respond to treatment. The cancer may be resistant at the beginning of treatment, or it may become resistant during treatment.
National Institutes of Health

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Related topics

2 relations
Neoplastic Cellcancer cell

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Accepted Manuscript Title : Long Non-coding RNAs : an Emerging Powerhouse in the Battle between Life and Death of Tumor Cells
Highly Cited
2009
Highly Cited
2009
Dose-Ranging Study of Metronomic Oral Vinorelbine in Patients with Advanced Refractory Cancer
Aim: To determine the safe dose range and pharmacokinetics of metronomic oral vinorelbine and obtain preliminary data on… 
Review
2006
Review
2006
Anti-galectin compounds as potential anti-cancer drugs.
Galectins form a family of carbohydrate-binding proteins defined by their affinity for beta-galactosides containing… 
Highly Cited
2004
Highly Cited
2004
Platinum(IV) complex with adamantylamine as nonleaving amine group: synthesis, characterization, and in vitro antitumor activity against a panel of cisplatin-resistant cancer cell lines.
Procedure of the synthesis is described for new platinum(IV) drug LA-12 [(OC-6-43)-bis(acetato)(1-adamantylamine… 
Review
2003
Review
2003
Targeting cancer cells by exploiting their resistance.
Highly Cited
2001
Highly Cited
2001
Inhibitory effect of steroidal alkaloids on drug transport and multidrug resistance in human cancer cells.
Intrinsic or acquired resistance of tumor cells to multiple cytotoxic drugs (multidrug resistance MDR) is a major cause of… 
Review
2001
Review
2001
Mechanisms of resistance to imatinib (STI571) and prospects for combination with conventional chemotherapeutic agents.
Imatinib (STI571, Glivec) is a small molecule drug selected for its ability to inhibit the Bcr-Abl kinase, the pathogenic… 
Highly Cited
1986
Highly Cited
1986
Administration of intraspinal morphine sulfate for the treatment of intractable cancer pain.
A total of 24 patients with intractable cancer pain were evaluated as candidates for spinal morphine therapy. Temporary trials… 
Highly Cited
1984
Highly Cited
1984
Improved control of bulky prostate carcinoma with sequential estrogen and radiation therapy.
Highly Cited
1981
Highly Cited
1981
High-dose combined-modality therapy and autologous bone marrow transplantation in resistant cancer.
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