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ramelteon

Known as: (S)-N-(2-(1,6,7,8-tetrahydro-2H-indeno-(5,4)furan-8-yl)ethyl)propionamide, ramelteon [Chemical/Ingredient] 
A synthetic melatonin analogue with hypnotic and circadian rhythm-modulating activities. Ramelteon binds to and activates melatonin receptors 1 and 2… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
IMPORTANCE No highly effective interventions to prevent delirium have been identified. OBJECTIVE To examine whether ramelteon… Expand
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Abnormalities in circadian rhythms are prominent features of bipolar disorder. Disrupted circadian rhythms are… Expand
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Review
2012
Review
2012
The pineal product melatonin has remarkable antioxidant properties. It is secreted during darkness and plays a key role in… Expand
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Review
2012
Review
2012
Melatonin is a highly pleiotropic signaling molecule, which is released as a hormone of the pineal gland predominantly during… Expand
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Highly Cited
2009
Highly Cited
2009
STUDY OBJECTIVES Long-duration (> or = 6 months) polysomnographic studies of insomnia medications are lacking. This study… Expand
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Review
2009
Review
2009
An estimated one‐third of the general population is affected by insomnia, and this number is increasing due to more stressful… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE To evaluate efficacy and safety of ramelteon (MT1/MT2-receptor [corrected] agonist) in subjects with chronic primary… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND AND PURPOSE To assess the efficacy and safety of ramelteon, a selective MT(1)/MT(2) receptor agonist, for chronic… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND AND PURPOSE To evaluate the efficacy, safety, and dose response of Ramelteon, a novel highly selective MT1/MT2… Expand
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Highly Cited
2005
Highly Cited
2005
Ramelteon (TAK-375) is a novel melatonin receptor agonist currently under investigation for the treatment of insomnia. This study… Expand
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