radiosensitization

The use of a drug that makes tumor cells more sensitive to radiation therapy.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Gold nanoparticles have been conceived as a radiosensitizer in cancer radiation therapy, but one of the important questions for… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE Gold nanoparticles (GNPs) have been shown to cause sensitization with kilovoltage (kV) radiation. Differences in the… (More)
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Highly Cited
2010
Highly Cited
2010
The median survival for patients with locally advanced pancreatic cancer treated with gemcitabine and radiation is approximately… (More)
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Highly Cited
2009
Highly Cited
2009
The metabolism of oxygen, although central to life, produces reactive oxygen species (ROS) that have been implicated in processes… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Poly(ADP-ribose) polymerase-1 (PARP-1) facilitates the repair of DNA strand breaks. Inhibiting PARP-1 increases the… (More)
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Highly Cited
2004
Highly Cited
2004
Curcumin (Diferuloylmethane) is a major chemical component of turmeric (curcuma longa) and is used as a spice to give a specific… (More)
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Highly Cited
2003
Highly Cited
2003
The DNA repair enzymes, DNA-dependent protein kinase (DNA-PK) and poly(ADP-ribose) polymerase-1 (PARP-1), are key determinants of… (More)
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Highly Cited
1999
Highly Cited
1999
Caffeine exposure sensitizes tumor cells to ionizing radiation and other genotoxic agents. The radiosensitizing effects of… (More)
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Highly Cited
1998
Highly Cited
1998
Members of the phosphatidylinositol-3 kinase related kinase (PIKK) family function in both cell cycle progression and DNA damage… (More)
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Highly Cited
1997
Highly Cited
1997
Members of the phosphatidylinositol (PI) 3-kinase gene family, including the ataxia telangiectasia gene and the DNA-dependent… (More)
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