r-metHuBDNF protein, recombinant

Known as: Recombinant Methionyl Human Brain-Derived Factor, methionyl human brain-derived neurotrophic factor, r-metHuBDNF 
A recombinant form of neurotrophic growth factor that regulates the development and maintenance of motor neurons expressing trk B receptor tyrosine… (More)
National Institutes of Health

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Brain-Derived Neurotrophic FactorRecombinant Proteins

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2001
2001
Disease status and use of ventilatory support by ALS patients. BDNF Study Group.
INTRODUCTION Use of mechanical ventilation (MV), administered either invasively via tracheostomy, or more commonly non-invasively… (More)
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Highly Cited
2000
Highly Cited
2000
A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis.
BACKGROUND Brain derived neurotrophic factor (BDNF) is a potent survival factor for motoneurons. This study investigated the… (More)
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Highly Cited
2000
Highly Cited
2000
Recombinant human neurotrophic factors accelerate colonic transit and relieve constipation in humans.
BACKGROUND & AIMS The aim of this study was to assess the effects of recombinant human brain-derived neurotrophic factor (r… (More)
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1997
1997
Kinetic and safety studies on intrathecally infused recombinant-methionyl human brain-derived neurotrophic factor in dogs.
To define the kinetics and safety of spinally infused recombinant-methionyl human brain-derived neurotrophic factor (r-metHuBDNF… (More)
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1996
1996
Use of a rodent neurotoxicity screening battery in the preclinical safety assessment of recombinant-methionyl human brain-derived neurotrophic factor.
Recent efforts to evaluate neurobehavioral function in adult rodents as part of preclinical safety studies have typically been… (More)
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