quinotrierixin
National Institutes of Health
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Purpose To investigate the effect of quinotrierixin, a previously reported inhibitor of X-box binding protein 1 (XBP1), on cell…
Methanethiol as a catabolite of methionine provides methylthio- group for chemical formation of 19- S -methylgeldanamycin and 17…
Quinotrierixin was isolated from microbes as an inhibitor of ER stress-induced XBP1 mRNA splicing, but its mode of action was…
In the course of screening for an inhibitor of ER stress-induced XBP1 activation, we isolated a new member of the triene…
Four novel triene-ansamycin group compounds, quinotrierixin, demethyltrienomycin A, demethyltrienomycin B and…