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quinoline analog

 
National Institutes of Health

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2019
2019
Quinoline analogs of 2-aminoindane as potential central dopaminergic agents
Neurodegenerative disorders such as Parkinson and Huntington Chorea are related with damage to the central dopaminergic system… Expand
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2014
2014
Zinc-specific intramolecular excimer formation in TQEN derivatives: fluorescence and zinc binding properties of TPEN-based hexadentate ligands.
Zn(2+)-induced fluorescence enhancement of the TPEN (N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine)-based ligand, N,N-bis(1… Expand
Highly Cited
2012
Highly Cited
2012
Inhibition of autophagy and induction of breast cancer cell death by mefloquine, an antimalarial agent.
Autophagy has been recognized as a potential target for cancer therapy. The antimalarial drug chloroquine (CQ) is able to inhibit… Expand
2010
2010
Synthesis, Cytotoxic and Antimalarial Activities of Benzoyl Thiosemicarbazone Analogs of Isoquinoline and Related Compounds
Thiosemicarbazone analogs of papaveraldine and related compounds 1–6 were synthesized and evaluated for cytotoxic and… Expand
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2010
2010
Quinoline-3-carboxamide containing sulfones as liver X receptor (LXR) agonists with binding selectivity for LXRbeta and low blood-brain penetration.
A series of quinoline-3-carboxamide containing sulfones was prepared and found to have good binding affinity for LXRbeta and… Expand
Highly Cited
2008
Highly Cited
2008
Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ
As a disease-modifying approach for Alzheimer's disease (AD), clioquinol (CQ) targets beta-amyloid (Abeta) reactions with… Expand
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1991
1991
SOLUBILIZATION SITES AND ACID‐BASE FORMS OF DIBUCAINE‐HYDROCHLORIDE IN NEUTRAL AND CHARGED MICELLAR SOLUTIONS
Steady‐state and time‐resolved emission spectroscopic techniques have been employed to characterize the drug species of dibucaine… Expand
1975
1975
Quinoline analog labeled with iodine 123 in melanoma detection.
Using the Greene melanoma in the hamster (Syrian Golden), the radiopharmaceutical, 123-1-4(3-dimethylaminopropylamino)-7… Expand
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