quelamycin

Supplemental orally-administered iron has been available for centuries, but parenteral administration of iron as a therapeutic… Expand

The title of this little assay coins three new words: Pre-Chelates, Post-Adducts and Implexes. These, very daring new excursions… Expand

Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Haste is a bad counselor when one is striving to… Expand

Male Sprague-Dawley rats were given a single dose of 10 or 20 mg/kg quelamycin intravenously and perfusion fixed at 4, 12, 28 and… Expand

Quelamycin is triferric doxorubicin, a metallic derivative of adriamycin which, in experimental studies, has been found to have a… Expand

Quelamycin (triferric doxorubicin) is a derivative of Adriamycin with different pharmacologic properties. Our phase I clinical… Expand

A previous phase I study demonstrated excessive generalized toxicity (20 of 21 patients) and cardiotoxicity (eight of 21 patients… Expand

Abstract Quelamycin is triferric doxorubicine, a metallic derivative of adriamycin made by chelation of adriamycin at neutral pH… Expand

Abstract We have performed a preliminary evaluation of a phase I clinical trial of quelamycin (triferric adriamycin) with 20… Expand

A phase I clinical study was done with quelamycin, a recently synthesized triferric derivative of adriamycin. Twenty-one good… Expand