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pyrrolidine-3-carboxylic acid

National Institutes of Health

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Pyrrolidines

Papers overview

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2019
2019
Application of the concept of oxime library screening by mass spectrometry (MS) binding assays to pyrrolidine-3-carboxylic acid derivatives as potential inhibitors of γ-aminobutyric acid transporter…
2013
2013
Alternating asymmetric self-induction in functionalized pyrrolidine oligomers.
Artificial structurally well-defined polymers have excited interest as functional mimetics of natural biomacromolecules… 
1999
1999
Design, synthesis, and activity of a series of pyrrolidine-3-carboxylic acid-based, highly specific, orally active ET(B) antagonists containing a diphenylmethylamine acetamide side chain.
The endothelin (ET)-B receptor subtype is expressed on vascular endothelial and smooth muscle cells and mediates both… 
1998
1998
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 3. Discovery of a potent, 2-nonaryl, highly selective ETA antagonist (A-216546).
Previously we have reported the discovery of ABT-627 (1, A-147627, active enantiomer of A-127722), a 2,4-diaryl substituted… 
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