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pyroglutamate helix B surface peptide

Known as: UEQLERALNSS, pHBSP peptide, pGlu-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser 
 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

ARA290

Broader (1)

Oligopeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Technetium-99 m-PEGylated dendrimer-G2-(Dabcyle-Lys6,Phe7)-pHBSP: A novel Nano-Radiotracer for molecular and early detecting of cardiac ischemic region.
In cardiac ischemic disorder, pyroglutamate helix B surface peptide (pHBSP) which derived from erythropoietin causes to increase… Expand
2016
2016
Erythropoietin and a nonerythropoietic peptide analog promote aortic endothelial cell repair under hypoxic conditions: role of nitric oxide
The cytoprotective effects of erythropoietin (EPO) and an EPO-related nonerythropoietic analog, pyroglutamate helix B surface… Expand
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2016
2016
192 Hypoxia Enhances the Reparative Effect of Tissue Protective Erythropoietin and Its Non-Erythropoietic Peptide Analogue in an Endothelial Cell Injury Model
Background Endothelial injury is a critical feature in the early stages of vascular disease. Inflammation and hypoxia are often… Expand
2015
2015
Low Oxygen Tension Primes Aortic Endothelial Cells to the Reparative Effect of Tissue-Protective Cytokines
Erythropoietin (EPO) has both erythropoietic and tissue-protective properties. The EPO analogues carbamylated EPO (CEPO) and… Expand
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2014
2014
A non‐erythropoietic peptide derivative of erythropoietin decreases susceptibility to diet‐induced insulin resistance in mice
The haematopoietic activity of erythropoietin (EPO) is mediated by the classic EPO receptor (EpoR) homodimer, whereas tissue… Expand
2013
2013
Treatment of mild traumatic brain injury with an erythropoietin-mimetic peptide.
Mild traumatic brain injury (mTBI) results in an estimated 75-90% of the 1.7 million TBI-related emergency room visits each year… Expand
2012
2012
Delayed Administration of Pyroglutamate Helix B Surface Peptide (pHBSP), a Novel Nonerythropoietic Analog of Erythropoietin, Attenuates Acute Kidney Injury
In preclinical studies, erythropoietin (EPO) reduces ischemia-reperfusion-associated tissue injury (for example, stroke… Expand
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2012
2012
Neuroprotection with an erythropoietin mimetic peptide (pHBSP) in a model of mild traumatic brain injury complicated by hemorrhagic shock.
Pyroglutamate helix B surface peptide (pHBSP) is an 11 amino acid peptide, designed to interact with a novel cell surface… Expand
Highly Cited
2011
Highly Cited
2011
A Small Nonerythropoietic Helix B Surface Peptide Based upon Erythropoietin Structure Is Cardioprotective against Ischemic Myocardial Damage
Strong cardioprotective properties of erythropoietin (EPO) reported over the last 10 years have been difficult to translate to… Expand
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Review
2010
Review
2010
Patent Evaluation Non-erythropoietic tissue-protective peptides derived from erythropoietin : WO 2009094172
Erythropoietin (EPO) is a cytokine with erythropoietic and tissue protective activities. Its action as a tissue protective agent… Expand
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