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pyridomycin

 
National Institutes of Health

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Oligopeptides

Papers overview

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2019
2019
Combating Antimicrobial Resistance in Singapore: A Qualitative Study Exploring the Policy Context, Challenges, Facilitators, and Proposed Strategies
Antimicrobial resistance (AMR) is a global public health threat that warrants urgent attention. However, the multifaceted nature… Expand
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2016
2016
Functional Characterization of PyrG, an Unusual Nonribosomal Peptide Synthetase Module from the Pyridomycin Biosynthetic Pathway.
Pyridomycin is an antimycobacterial cyclodepsipeptide assembled by a nonribosomal peptide synthetase/polyketide synthase hybrid… Expand
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2014
2014
Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA.
Pyridomycin, a natural product with potent antituberculosis activity, inhibits a major drug target, the InhA enoyl reductase… Expand
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2013
2013
Synthesis and antimycobacterial activity of 2,1'-dihydropyridomycins.
Dihydropyridomycins 2 and 3, which lack the characteristic enol ester moiety of the potent antimycobacterial natural product… Expand
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Highly Cited
2012
Highly Cited
2012
Towards a new tuberculosis drug: pyridomycin – nature's isoniazid
Tuberculosis, a global threat to public health, is becoming untreatable due to widespread drug resistance to frontline drugs such… Expand
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2011
2011
Identification and characterization of the pyridomycin biosynthetic gene cluster of Streptomyces pyridomyceticus NRRL B-2517.
Pyridomycin is a structurally unique antimycobacterial cyclodepsipeptide containing rare 3-(3-pyridyl)-l-alanine and 2-hydroxy-3… Expand
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2011
2011
Identification and Characterization of the Pyridomycin Biosynthetic Gene Cluster of Streptomyces pyridomyceticus
Pyridomycin is a structurally unique antimycobacterial cyclodepsipeptide containing rare 3-(3-pyridyl)-L-alanine and 2-hydroxy-3… Expand
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1968
1968
The biosynthesis of pyridomycin. I.
 
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1955
1955
Studies on the pyridomycin production. II. X-ray irradiation on the pyridomycin-producing strain.
Antimicrobial resistance (AMR) is a global public health threat that warrants urgent attention. However, the multifaceted nature… Expand
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1953
1953
A new antibiotic, pyridomycin.
 
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