pyridinoline

Known as: Hydroxylysylpyridinoline, Pyridinium, 4-(2-amino-2-carboxyethyl)-1-(5-amino-5-carboxy-2-hydroxypentyl)-3-(3-amino-3-carboxypropyl)-5-hydroxy-, hydroxide, inner salt, hydroxylysyl pyridinoline 
A non-reducible crosslinker for collagen. This compound is fluorescent and is found in mature bone and cartilage collagens. Pyridinoline found in the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Fibrosis is characterized by an excessive accumulation of collagen which contains increased levels of pyridinoline cross-links… (More)
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Highly Cited
2003
Highly Cited
2003
The hallmark of fibrotic processes is an excessive accumulation of collagen. The deposited collagen shows an increase in… (More)
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Highly Cited
2002
Highly Cited
2002
The hypothesis of this study is that the mechanical integrity of the collagen network in bone deteriorates with age, and such… (More)
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Highly Cited
1998
Highly Cited
1998
Fracture of the proximal femur is the most dramatic clinical sequela of osteoporosis [1, 2]. It is associated with a high… (More)
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Highly Cited
1996
Highly Cited
1996
A major contribution to the mechanical strength of the heart is provided by a continuous fibrillar collagen network embracing… (More)
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1996
1996
Compared with soft tissue collagens, bone type I collagen displays a distinctive pattern of covalent cross-linking, with evidence… (More)
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Highly Cited
1994
Highly Cited
1994
To evaluate the clinical utility of recently developed biochemical markers of bone turnover to monitor the response of… (More)
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Highly Cited
1993
Highly Cited
1993
We developed a radioimmunoassay (RIA) for the carboxy-terminal telopeptides of type I collagen (ICTP), cross-linked with the… (More)
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1993
1993
Urinary pyridinoline (Pyd) and deoxypyridinoline (Dpd) are markers of bone resorption that are elevated above normal in subjects… (More)
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Highly Cited
1992
Highly Cited
1992
Peptides of low molecular weight that contain pyridinoline cross-links were isolated from adolescent human urine. A fraction was… (More)
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