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pyrazolanthrone

Known as: 1,9-pyrazoloanthrone, 2h-dibenzo(cd,g)indazol-6-one, anthra(1,9-cd)pyrazol-6(2H)-one 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Anthracenes

Narrower (1)

SP600125

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Inflammatory Mediators Increase SUMOylation of Retinoid X Receptor α in a c-Jun N-Terminal Kinase–Dependent Manner in Human Hepatocellular Carcinoma Cells
Retinoid X receptor α [RXRα; nuclear receptor (NR)2B1] is a crucial regulator in the expression of a broad array of hepatic genes… 
2011
2011
Inhibitory Effects of Microwave Radiation on LPS-Induced NFκB Expression in THP-1 Monocytes.
Microwave radiations can be encountered regularly in daily lives. When WHO announced that microwave radiations were a kind of… 
Highly Cited
2010
Highly Cited
2010
Down‐regulation of MMP‐2 through the p38 MAPK‐NF‐κB‐dependent pathway by aloe‐emodin leads to inhibition of nasopharyngeal carcinoma cell invasion
Aloe‐emodin (AE), extracted from the rhizome of Rheum palmatum, has an anti‐proliferative effect on different human cancer cell… 
Highly Cited
2010
Highly Cited
2010
Regulation of Multidrug Resistance Protein 1 by Tumor Necrosis Factor α in Cultured Glial Cells: Involvement of Nuclear Factor-κB and c-Jun N-Terminal Kinase Signaling Pathways
Pharmacotherapy of brain HIV-1 infection may be limited by ABC transporters [i.e., P-glycoprotein (P-gp), multidrug resistance… 
Highly Cited
2007
Highly Cited
2007
1,1-Bis(3′-Indolyl)-1-(p-substitutedphenyl)methanes Inhibit Growth, Induce Apoptosis, and Decrease the Androgen Receptor in LNCaP Prostate Cancer Cells through Peroxisome Proliferator-Activated…
1,1-Bis(3′-indolyl)-1-(p-substitutedphenyl)methanes (C-DIMs) containing para-trifluoromethyl, t-butyl, and phenyl groups are a… 
Highly Cited
2006
Highly Cited
2006
Disruption of JNK2 Decreases the Cytokine Response to Plasmodium falciparum Glycosylphosphatidylinositol In Vitro and Confers Protection in a Cerebral Malaria Model1
Host inflammatory responses to Plasmodium falciparum GPI (pfGPI) anchors are believed to play an important role in the… 
Highly Cited
2006
Highly Cited
2006
Busulfan Selectively Induces Cellular Senescence but Not Apoptosis in WI38 Fibroblasts via a p53-Independent but Extracellular Signal-Regulated Kinase-p38 Mitogen-Activated Protein Kinase-Dependent…
Busulfan (BU) is a unique alkylating agent that primarily targets slowly proliferating or nonproliferating cells in the body… 
Highly Cited
2006
Highly Cited
2006
JNK inhibitor SP600125 reduces COX-2 expression by attenuating mRNA in activated murine J774 macrophages.
2006
2006
Identification of the Insulin Signaling Cascade in the Regulation of Alpha-Class Glutathione S-Transferase Expression in Primary Cultured Rat Hepatocytes
We reported previously that insulin elevated alpha-class glutathione S-transferase (GSTs) protein levels in primary cultured rat… 
Highly Cited
2005
Highly Cited
2005
Pro- and anti-apoptotic roles of c-Jun N-terminal kinase (JNK) in ethanol and acetaldehyde exposed rat hepatocytes.
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