purvalanol A

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2018
02420002018

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2013
2013
Cyclin-dependent kinase inhibitors (CDKi) have high potential applicability in anticancer therapy, but various aspects of their… (More)
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2012
2012
Inhibition of cyclin-dependent kinases by specific small molecules, purine cyclin-dependent kinase inhibitors (CDKi), has become… (More)
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2012
2012
Although preconditioning injury on the peripheral nerve induces axonal regenerative capacity in neurons, it is not known whether… (More)
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2010
2010
BACKGROUND Histone deacetylase inhibitors (HDACis) are promising anticancer drugs; however, the molecular mechanisms leading to… (More)
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2010
2010
The nonreceptor tyrosine kinase c-Src is frequently over-expressed or hyperactivated in various human cancers and contributes to… (More)
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2008
2008
Human T-cell leukemia virus type-1 (HTLV-1) induces adult T-cell leukemia/lymphoma (ATL/L), a fatal lymphoproliferative disorder… (More)
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2005
2005
Cleavage furrow formation marks the onset of cell division during early anaphase. The small GTPase RhoA and its regulators ECT2… (More)
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2005
2005
Initial chemotherapeutic treatment triggers a stress-related response, which can lead to an increase in the expression of… (More)
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2005
2005
Cyclin-dependent kinases (CDK) play a crucial role in the control of the cell cycle. Aberrations in the control of cell cycle… (More)
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2002
2002
We have studied the effects of purvalanol A on the cell cycle progression, proliferation and viability. In synchronized cells… (More)
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