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purinoceptor P2Y6

Known as: P2Y6 receptor, receptor, P2Y(6), receptor, P2Y6 
National Institutes of Health

Related topics

Related topics

2 relations
P2RY6 gene

Broader (1)

Receptors, Purinergic P2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Purinergic P2Y6 receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II–induced hypertension
Aging changes the response of blood vessels to angiotensin II, contributing to hypertension. Raising blood pressure with age… 
2016
2016
Marsdeniae tenacissimae extract (MTE) suppresses cell proliferation by attenuating VEGF/VEGFR2 interactions and promotes apoptosis through regulating PKC pathway in human umbilical vein endothelial…
2015
2015
Synthesis and structure-activity relationship of uracil nucleotide derivatives towards the identification of human P2Y6 receptor antagonists.
2015
2015
Protein Interacting C-Kinase 1 Modulates Surface Expression of P2Y6 Purinoreceptor, Actin Polymerization and Phagocytosis in Microglia
Microglia clean up dead cells and debris through phagocytosis in the central nervous system. UDP-activated P2Y6 receptors (P2Y6Rs… 
2015
2015
Molecular and cellular pharmacology Inhibition of P 2 Y 6 receptor-mediated phospholipase C activation and Ca 2 þ signalling by prostaglandin E 2 in J 774 murine macrophages
Extracellular nucleotides act as inflammatory mediators through activation of multiple purinoceptors. Under inflammatory… 
Highly Cited
2014
Highly Cited
2014
Inhibition of UDP/P2Y6 purinergic signaling prevents phagocytosis of viable neurons by activated microglia in vitro and in vivo
Microglia activated through Toll‐like receptor (TLR)‐2 or ‐4 can cause neuronal death by phagocytosing otherwise‐viable neurons—a… 
2014
2014
Enhancement of Glucose Uptake in Mouse Skeletal Muscle Cells and Adipocytes by P2Y6 Receptor Agonists
Glucose uptake by peripheral tissues such as skeletal muscles and adipocytes is important in the maintenance of glucose… 
2013
2013
AMP-activated protein kinase as regulator of P2Y(6) receptor-induced insulin secretion in mouse pancreatic β-cells.
2004
2004
Characterization of the biological activities of uridine diphosphate in human dendritic cells: Influence on chemotaxis and CXCL8 release.
Uridine nucleotides are endogenous nucleotides which are released into the extracellular space from mechanical stressed… 
Highly Cited
2001
Highly Cited
2001
Differential Regulation of the Uridine Nucleotide-activated P2Y4 and P2Y6 Receptors
Agonist-promoted regulation of the uridine nucleotide-activated human P2Y4 receptor (P2Y4-R) and P2Y6 receptor (P2Y6-R) was… 
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