pseudoisocytosine
National Institutes of Health
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Chemically-modified short Peptide Nucleic Acids (PNAs) recognize RNA duplexes at near physiological conditions by major-groove…
Peptide nucleic acids (PNAs) have been developed for applications in biotechnology and therapeutics. There is great potential in…
We describe the development of templated fluorogenic chemistry for detection of specific sequences of duplex DNA in solution. In…
Abstract A novel synthesis of 2′-deoxypseudoisocytidine as well as of its phosphoramidite building block for oligonucleotide…
The synthesis of N-[2-(N-9-fluorenylmethoxycarbonyl)aminoethyl]-N-(2-N-(benzyloxycarbonyl)isocytosin-5-ylacetyl)glycine monomer…
The formation of a DNA "paper-clip" type triple helix (triplex) with a common sequence 5'-d-(TC)(3)T(a)()(CT)(3)C(b)()(AG)(3) (a…
Strand displacement binding kinetics of cationic pseudoisocytosine-containing linked homopyrimidine peptide nucleic acids (bis…