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psammaplin A

Known as: bisprasin 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

DisulfidesTyrosine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Triggering of Suicidal Erythrocyte Death by Psammaplin A
Background/Aims: Psammaplin A, a natural product isolated from marine sponges, triggers apoptosis of tumor cells and is thus… 
2013
2013
Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors
Summary There has been significant interest in the bioactivity of the natural product psammaplin A, most recently as a potent and… 
2013
2013
Psammaplin A inhibits hepatitis C virus NS3 helicase
Hepatitis C virus (HCV) is the causative agent of hepatitis C, a chronic infectious disease that can lead to development of… 
Highly Cited
2008
Highly Cited
2008
A natural histone deacetylase inhibitor, Psammaplin A, induces cell cycle arrest and apoptosis in human endometrial cancer cells.
Highly Cited
2007
Highly Cited
2007
Psammaplin A is a natural prodrug that inhibits class I histone deacetylase
Histone deacetylase (HDAC) has been highlighted as one of key players in tumorigenesis and angiogenesis. Recently, several… 
Highly Cited
2004
Highly Cited
2004
Cytotoxicity of psammaplin A from a two-sponge association may correlate with the inhibition of DNA replication
BackgroundSV40 DNA replication system is a very useful tool to understand the mechanism of replication, which is a tightly… 
Review
2003
Review
2003
The discovery of NVP-LAQ824: from concept to clinic.
The natural products trapoxin B and trichostatin A, as well as the novel marine natural product psammaplin A (PSMA) were found in… 
Highly Cited
2001
Highly Cited
2001
Combinatorial synthesis through disulfide exchange: discovery of potent psammaplin A type antibacterial agents active against methicillin-resistant Staphylococcus aureus (MRSA).
Psammaplin A is a symmetrical bromotyrosine-derived disulfide natural product isolated from the Psammaplysilla sponge, which… 
Highly Cited
1999
Highly Cited
1999
Psammaplin A, a natural bromotyrosine derivative from a sponge, possesses the antibacterial activity against methicillin-resistantStaphylococcus aureus and the DNA gyrase-inhibitory activity
Psammaplin A, a natural bromotyrosine derivative from an associated form of two sponges (Poecillastra sp. andJaspis sp.) was… 
Highly Cited
1999
Highly Cited
1999
Psammaplin A, a natural phenolic compound, has inhibitory effect on human topoisomerase II and is cytotoxic to cancer cells.
We evaluated the topoisomerase II (Topo II) inhibitory activity of psammaplin A (PSA), a naturally occurring biphenolic compound… 
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