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protoberberine

Known as: 2,3,11-trimethoxy-5,6,13,13a-tetrahydro-8H-dibenzo(a,g)quinolizine 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Berberine Alkaloids

Narrower (1)

protoberberine iodide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
Molecular aspects on the interaction of protoberberine, benzophenanthridine, and aristolochia group of alkaloids with nucleic acid structures and biological perspectives
Alkaloids occupy an important position in chemistry and pharmacology. Among the various alkaloids, berberine and coralyne of the… 
Highly Cited
2007
Highly Cited
2007
Poppy alkaloid profiling by electrospray tandem mass spectrometry and electrospray FT-ICR mass spectrometry after [ring-13C6]-tyramine feeding.
2007
2007
Leishmania panamensis: comparative inhibition of nuclear DNA topoisomerase II enzymes from promastigotes and human macrophages reveals anti-parasite selectivity of fluoroquinolones, flavonoids and…
Highly Cited
2006
Highly Cited
2006
Molecular aspects on the specific interaction of cytotoxic plant alkaloid palmatine to poly(A).
Highly Cited
2004
Highly Cited
2004
Interaction of benzo[c]phenanthridine and protoberberine alkaloids with animal and yeast cells
We compared the effects of four quaternary benzo[c]phenanthridine alkaloids – chelerythrine, chelilutine, sanguinarine, and… 
Highly Cited
2004
Highly Cited
2004
A versatile total synthesis of benzo[c]phenanthridine and protoberberine alkaloids using lithiated toluamide-benzonitrile cycloaddition.
A new versatile synthesis of benzo[c]phenanthridine and protoberberine alkaloids using lithiated toluamide-benzonitrile… 
Highly Cited
1997
Highly Cited
1997
Minor groove-directed and intercalative ligand-DNA interactions in the poisoning of human DNA topoisomerase I by protoberberine analogs.
Spectroscopic, calorimetric, DNA cleavage, electrophoretic, and computer modeling techniques have been employed to characterize… 
Highly Cited
1996
Highly Cited
1996
Identification of topoisomerase I as the cytotoxic target of the protoberberine alkaloid coralyne.
Protoberberine alkaloids (coralyne and its derivatives), which exhibit antileukemic activity in animal models, have been shown to… 
1992
1992
HIV-1 and HIV-2 reverse transcriptases: a comparative study of sensitivity to inhibition by selected natural products.
Highly Cited
1983
Highly Cited
1983
Attenuation of alcohol drinking in tetrahydroisoquinoline-treated rats by morphine and naltrexone
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