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protoberberine

Known as: 2,3,11-trimethoxy-5,6,13,13a-tetrahydro-8H-dibenzo(a,g)quinolizine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1962-2018
05101519622018

Related topics

Related topics

2 relations

Broader (1)

Berberine Alkaloids

Narrower (1)

protoberberine iodide

Related mentions per year

Related mentions per year

1956-2018
1960198020002020
protoberberine
Berberine Alkaloids
protoberberine iodide

Papers overview

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2015
2015
Optimization of yeast-based production of medicinal protoberberine alkaloids
BACKGROUND Protoberberine alkaloids are bioactive molecules abundant in plant preparations for traditional medicines. Yeast… (More)
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2008
2008
Binding of protoberberine alkaloid coralyne with double stranded poly(A): a biophysical study.
Recognition of double stranded ribonucleic acid is a critical event in many biological pathways such as trafficking, editing and… (More)
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2007
2007
Amplification of DNA-binding affinities of protoberberine alkaloids by appended polyamines.
This communication describes a synthetic approach toward the amplification of the moderate DNA-binding affinities of… (More)
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2007
2007
Inhibition of DNA topoisomerase I by natural and synthetic mono- and dimeric protoberberine alkaloids.
A series of natural (i.e., 1-7) and synthetic (i.e., 8-23) protoberberine alkaloids were evaluated for their inhibitory… (More)
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2005
2005
Cell type-specific localization of transcripts encoding nine consecutive enzymes involved in protoberberine alkaloid biosynthesis.
Molecular clones encoding nine consecutive biosynthetic enzymes that catalyze the conversion of l-dopa to the protoberberine… (More)
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2003
2003
Positive cooperation of protoberberine type 2 alkaloids from Corydalis cava on the GABA(A) binding site.
Protoberberine alkaloids from the rhizomes of Corydalis cava were investigated with regard to their influence on the GABA A… (More)
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2001
2001
In vitro cytotoxicity of the protoberberine-type alkaloids.
In vitro cytotoxic activities of 24 quaternary protoberberine alkaloids related to berberine have been evaluated using a human… (More)
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2000
2000
Human topoisomerase I poisoning by protoberberines: potential roles for both drug-DNA and drug-enzyme interactions.
Protoberberines represent a structural class of organic cations that induce topoisomerase I-mediated DNA cleavage, a behavior… (More)
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1998
1998
Induction of topoisomerase II-mediated DNA cleavage by a protoberberine alkaloid, berberrubine.
Topoisomerase II is the cytotoxic target for a number of clinically relevant antitumor drugs. Berberrubine, a protoberberine… (More)
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1983
1983
Enzyme inhibition VI: Inhibition of reverse transcriptase activity by protoberberine alkaloids and structure-activity relationships.
Protoberberine alkaloids such as palmatine (I), 13-methylpalmatine iodide (II), 2,3-methylenedioxy-10,11-dimethoxy-13… (More)
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