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protoberberine

Known as: 2,3,11-trimethoxy-5,6,13,13a-tetrahydro-8H-dibenzo(a,g)quinolizine 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Berberine Alkaloids

Narrower (1)

protoberberine iodide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
RNA targeting through binding of small molecules: Studies on t-RNA binding by the cytotoxic protoberberine alkaloid coralyne.
Interaction of the protoberberine alkaloid coralyne with t-RNA(phe) was investigated using various biophysical techniques… Expand
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Highly Cited
2008
Highly Cited
2008
Microbial production of plant benzylisoquinoline alkaloids.
Benzylisoquinoline alkaloids, such as the analgesic compounds morphine and codeine, and the antibacterial agents berberine… Expand
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Highly Cited
2006
Highly Cited
2006
Free radical scavenging activity and lipoxygenase inhibition of Mahonia aquifolium extract and isoquinoline alkaloids
Roots and stem-bark of Mahonia aquifolium (Oregon grape) (Berberidaceae) are effectively used in the treatment of skin… Expand
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2005
2005
Cell type-specific localization of transcripts encoding nine consecutive enzymes involved in protoberberine alkaloid biosynthesis.
Molecular clones encoding nine consecutive biosynthetic enzymes that catalyze the conversion of l-dopa to the protoberberine… Expand
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2004
2004
Interaction of benzo[c]phenanthridine and protoberberine alkaloids with animal and yeast cells
We compared the effects of four quaternary benzo[c]phenanthridine alkaloids – chelerythrine, chelilutine, sanguinarine, and… Expand
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Highly Cited
2002
Highly Cited
2002
Inhibitory effect of berberine on tert-butyl hydroperoxide-induced oxidative damage in rat liver
Abstract. Berberine, a main protoberberine component of Coptidis Rhizoma, was studied for the mechanism of its inhibitory effects… Expand
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2000
2000
Human topoisomerase I poisoning by protoberberines: potential roles for both drug-DNA and drug-enzyme interactions.
Protoberberines represent a structural class of organic cations that induce topoisomerase I-mediated DNA cleavage, a behavior… Expand
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Highly Cited
1996
Highly Cited
1996
Study on the anti-inflammatory action of Berberis vulgaris root extract, alkaloid fractions and pure alkaloids.
Extracts obtained from the roots of Berberidaceae species have been used in Eastern and Bulgarian folk medicine in rheumatic and… Expand
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1996
1996
Identification of topoisomerase I as the cytotoxic target of the protoberberine alkaloid coralyne.
Protoberberine alkaloids (coralyne and its derivatives), which exhibit antileukemic activity in animal models, have been shown to… Expand
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1988
1988
Protoberberine alkaloids as antimalarials.
The protoberberine alkaloids berberine (1), palmatine (2), jatrorrhizine (3), and several berberine derivatives (4-10) were… Expand
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