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protoberberine

Known as: 2,3,11-trimethoxy-5,6,13,13a-tetrahydro-8H-dibenzo(a,g)quinolizine 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Berberine Alkaloids

Narrower (1)

protoberberine iodide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
A General Cp*CoIII -Catalyzed Intramolecular C-H Activation Approach for the Efficient Total Syntheses of Aromathecin, Protoberberine, and Tylophora Alkaloids.
Herein, we report a Cp*CoIII -catalyzed C-H activation approach as the key step to create highly valuable isoquinolones and… 
Review
2010
Review
2010
Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders
Berberine, an isoquinoline alkaloid of the protoberberine type found in an array of plants, has been used in Indian and Chinese… 
Review
2009
Review
2009
Berberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations.
ETHNOPHARMACOLOGICAL RELEVANCE Coptidis rhizoma (huanglian) and its major component, berberine, have drawn extensive attention… 
Review
2009
Review
2009
A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs
Natural products represent a rich reservoir of potential small chemical molecules exhibiting antiproliferation and anticancer… 
Highly Cited
2009
Highly Cited
2009
RNA targeting through binding of small molecules: Studies on t-RNA binding by the cytotoxic protoberberine alkaloid coralyne.
Interaction of the protoberberine alkaloid coralyne with t-RNA(phe) was investigated using various biophysical techniques… 
Highly Cited
2008
Highly Cited
2008
Microbial production of plant benzylisoquinoline alkaloids
Benzylisoquinoline alkaloids, such as the analgesic compounds morphine and codeine, and the antibacterial agents berberine… 
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Review
2007
Review
2007
Quaternary protoberberine alkaloids.
This contribution reviews some general aspects of the quaternary iminium protoberberine alkaloids. The alkaloids represent a very… 
Review
2007
Review
2007
Molecular aspects on the interaction of protoberberine, benzophenanthridine, and aristolochia group of alkaloids with nucleic acid structures and biological perspectives
Alkaloids occupy an important position in chemistry and pharmacology. Among the various alkaloids, berberine and coralyne of the… 
Highly Cited
1996
Highly Cited
1996
Identification of topoisomerase I as the cytotoxic target of the protoberberine alkaloid coralyne.
Protoberberine alkaloids (coralyne and its derivatives), which exhibit antileukemic activity in animal models, have been shown to… 
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Highly Cited
1988
Highly Cited
1988
Protoberberine alkaloids as antimalarials.
The protoberberine alkaloids berberine (1), palmatine (2), jatrorrhizine (3), and several berberine derivatives (4-10) were… 
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