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protein kinase B signaling

Known as: AKT signal transduction, PKB signaling, AKT signaling 
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Role of PKB/SGK-dependent phosphorylation of GSK-3α/β in vascular calcification during cholecalciferol overload in mice.
2013
2013
Błąd pomiaru czy błędna koncepcja. Kilka uwag na temat metodologii pomiaru dobrobytu - refleksja nt. książki błąd pomiaru. dlaczego PKB nie wystarcza? (J.E. Stiglitz, 2013)
2010
2010
Synthesis and structure-activity relationship studies of peptidomimetic PKB/Akt inhibitors: the significance of backbone interactions.
2009
2009
Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase.
The mechanism of the enzyme benzoylformate decarboxylase (BFDC), which carries out a typical thiamin diphosphate (ThDP)-dependent… 
2005
2005
Regulation of protein kinase B tyrosine phosphorylation by thyroid-specific oncogenic RET/PTC kinases.
Papillary thyroid carcinoma (PTC) is a heterogenous disorder characterized by unique gene rearrangements and gene mutations that… 
2005
2005
Expression and purification of active PKB kinase from Escherichia coli.
Highly Cited
2003
Highly Cited
2003
Promotion of mitosis by activated protein kinase B after DNA damage involves polo-like kinase 1 and checkpoint protein CHFR.
The role of the protein kinase B (PKB/Akt) in the regulation of cell survival and proliferation is well established. PKB is a key… 
2003
2003
Specific beta1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A.
Integrin transmembrane receptors generate multiple signals, but how they mediate specific signaling is not clear. Here we test… 
Highly Cited
2000
Highly Cited
2000
Effect of Phosphoinositide-Dependent Kinase 1 on Protein Kinase B Translocation and Its Subsequent Activation
ABSTRACT In this report we investigated the function of phosphoinositide-dependent protein kinase 1 (PDK1) in protein kinase B… 
Highly Cited
1998
Highly Cited
1998
Involvement of the Pleckstrin Homology Domain in the Insulin-stimulated Activation of Protein Kinase B*
Involvement of the pleckstrin homology (PH) domain in the insulin-stimulated activation of protein kinase B (PKB) was… 
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