protein kinase B signaling

Known as: AKT signal transduction, PKB signaling, AKT signaling 
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Insulin modulates glucose disposal in muscle and adipose tissue by regulating the cellular redistribution of the GLUT4 glucose… (More)
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Highly Cited
2005
Highly Cited
2005
Endurance training induces a partial fast-to-slow muscle phenotype transformation and mitochondrial biogenesis but no growth. In… (More)
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Highly Cited
2003
Highly Cited
2003
Ceramide is generated in response to numerous stress-inducing stimuli and has been implicated in the regulation of diverse… (More)
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Highly Cited
2002
Highly Cited
2002
Reactive oxygen species are required for cell proliferation but can also induce apoptosis. In proliferating cells this paradox is… (More)
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Highly Cited
2002
Highly Cited
2002
In adipocytes, protein kinase B (PKB) has been suggested to be the enzyme that phosphorylates phosphodiesterase 3B (PDE3B), a key… (More)
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Highly Cited
2001
Highly Cited
2001
The phosphatidylinositol 3-kinase (PI 3-kinase)/protein kinase B (PKB; also known as Akt) signalling pathway is recognized as… (More)
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2000
2000
In this report we investigated the function of phosphoinositide-dependent protein kinase 1 (PDK1) in protein kinase B (PKB… (More)
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2000
2000
Insulin receptor substrate (IRS) proteins are tyrosine phosphorylated and mediate multiple signals during activation of the… (More)
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Highly Cited
1999
Highly Cited
1999
L6 myoblasts stably transfected with a GLUT4 cDNA harboring an exofacial myc epitope tag (L6-GLUT4myc myoblasts) were used to… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The activation of protein kinase B (PKB, also known as c-Akt) is stimulated by insulin or growth factors and results… (More)
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