protein acylation

Known as: protein amino acid acylation 
The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid. [GOC:jl]
National Institutes of Health

Papers overview

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2019
2019
Quantifying competition among mitochondrial protein acylation events induced by ethanol metabolism.
Mitochondrial dysfunction is one of many key factors in the etiology of alcoholic liver disease (ALD). Lysine acetylation is… (More)
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Review
2018
Review
2018
The Causes and Consequences of Nonenzymatic Protein Acylation.
Thousands of protein acyl modification sites have now been identified in vivo. However, at most sites the acylation stoichiometry… (More)
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2017
2017
A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation.
The mechanisms underlying the formation of acyl protein modifications remain poorly understood. By investigating the reactivity… (More)
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2014
2014
Aberrant protein acylation is a common observation in inborn errors of acyl-CoA metabolism
Inherited disorders of acyl-CoA metabolism, such as defects in amino acid metabolism and fatty acid oxidation can present with… (More)
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2014
Review
2014
Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases.
Cellular proteins are decorated with a wide range of acetyl and other acyl modifications. Many studies have demonstrated… (More)
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2010
2010
Glucose stimulation of protein acylation in the pancreatic β-cell.
AIMS To determine whether protein acylation plays a role in the effects of glucose on the insulin secreting β-cell. MAIN… (More)
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2007
2007
The inhibitors of protein acylation, cerulenin and tunicamycin, increase voltage-dependent Ca(2+) currents in the insulin-secreting INS 832/13 cell.
As it has been suggested that protein acylation plays a role in nutrient stimulus-secretion coupling in the pancreatic beta-cell… (More)
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2002
2002
Protein acylation in the cardiac muscle like cell line, H9c2
Besides serving as oxidisable substrates, fatty acids (FA) are involved in co- and post-translational modification of proteins… (More)
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2000
2000
Cerulenin, an inhibitor of protein acylation, selectively attenuates nutrient stimulation of insulin release: a study in rat pancreatic islets.
Nutrients such as glucose stimulate insulin release from pancreatic beta-cells through both ATP-sensitive K+ channel-independent… (More)
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1999
1999
Protein acylation in normoxic and ischemic/reperfused cardiac tissue.
In addition to a prominent role in tissue energy conversion, fatty acids are involved in signal transduction and modulation of… (More)
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