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protamine 2

 
National Institutes of Health

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Review
2018
Review
2018
......................................................................................................................................... 2 Acknowledgments .......................................................................................................................... 3 List of figures ................................................................................................................................. 6 Introduction .................................................................................................................................... 7 Histone replacement: An overview .................................................................................... 7 Transition nuclear proteins (TNPs) .................................................................................... 9 Protamines (PRMs)........................................................................................................... 10 Functional relationship ..................................................................................................... 12 Introduction to methods and results ................................................................................. 13 Materials and methods ................................................................................................................. 15 Producing primary alignments ......................................................................................... 15 Testing predicted mRNA variants for PRM2 .................................................................. 18 Resolving abnormal sequence alignments ....................................................................... 21 Uncovering patterns of evolution ..................................................................................... 26 Mapping replacements on phylogenetic trees .................................................................. 27 Results .......................................................................................................................................... 33 Protein and gene sequence overview................................................................................ 33 Transition nuclear protein 1 (TNP1) ................................................................................ 34 Transition nuclear protein 2 (TNP2) ................................................................................ 39 Protamine 1 (PRM1) ........................................................................................................ 39 Protamine 2 (PRM2) ........................................................................................................ 40 Protamine 3 (PRM3) .........................................................................................................43 
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Review
2011
Review
2011
Protamine 2 (P2) is synthesised as a precursor protein (pre-P2) which by proteolysis is processed to generate the mature… Expand
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2011
2011
Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25), a testis-specific member of the DEAD-box family, is an essential… Expand
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1992
1992
Protamine 2 (PRM2) is a low molecular weight arginine-rich protein which is present in haploid spermatogenic cells of human and… Expand
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