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propiolaldehyde

Known as: 2-propynal 
National Institutes of Health

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1 relation

Broader (1)

Aldehydes

Papers overview

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2004
2004
NMR chemical shifts. Substituted acetylenes.
The MPW1PW91/6-311+G(2d,p) and MP2/6-311+G(2d,p) GIAO nuclear shieldings for a series of monosubstituted acetylenes have been… 
2001
2001
Cytochrome P450 2E1 metabolically activates propargyl alcohol: propiolaldehyde-induced hepatocyte cytotoxicity.
2000
2000
Identification of metabolites of [1,2,3-(13)C]Propargyl alcohol in mouse urine by (13)C NMR and mass spectrometry and comparison to rat.
Species differences in the metabolism of acetylenic compounds commonly used in the formulation of pharmaceuticals and pesticides… 
1986
1986
Role of propiolaldehyde and other metabolites in the pargyline inhibition of rat liver aldehyde dehydrogenase.
1985
1985
The metabolic fate of pargyline in rat liver microsomes.
1982
1982
Pargyline-induced hepatotoxicity: possible mediation by the reactive metabolite, propiolaldehyde.
1980
1980
Microsomal N-depropargylation of pargyline to propiolaldehyde, an irreversible inhibitor of mitochondrial aldehyde dehydrogenase.
Rat liver microsomes catalyzed the conversion of pargyline (N-methyl-N-propargylbenzylamine) to propiolaldehyde, a potent… 
1980
1980
Metabolic depropargylation and its relationship to aldehyde dehydrogenase inhibition in vivo.
The relationship between metabolic depropargylation in vitro to inhibition of the low Km aldehyde dehydrogenase (AIDH) of rat… 
1979
1979
Propiolaldehyde, a pargyline metabolite that irreversibly inhibits aldehyde dehydrogenase. Isolation from a hepatic microsomal system.
1978
1978
Inhibition of aldehyde dehydrogenase by propiolaldehyde, a possible metabolite of pargyline.
Pargyline (Eutonyl) inhibited aldehyde dehydrogenase (AlDH) in vivo in rats as adduced by the elevation of ethanol-derived blood… 
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