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propiolaldehyde
Known as:
2-propynal
National Institutes of Health
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1 relation
Broader (1)
Aldehydes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
N-Propargylamine protects SH-SY5Y cells from apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, through stabilization of mitochondrial membrane and induction of anti-apoptotic Bcl…
H. Yi
,
W. Maruyama
,
+4 authors
M. Naoi
Journal of neural transmission
2005
Corpus ID: 22626932
Summary.Propargylamine derivatives, rasagiline and (–)deprenyl, are anti-Parkinson agents and protect neurons from cell death as…
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2000
2000
Identification of metabolites of [1,2,3-(13)C]Propargyl alcohol in mouse urine by (13)C NMR and mass spectrometry and comparison to rat.
A. Banijamali
,
Y. Xu
,
V. DeMatteo
,
R. J. Strunk
,
S. Sumner
Journal of Agricultural and Food Chemistry
2000
Corpus ID: 23171872
Species differences in the metabolism of acetylenic compounds commonly used in the formulation of pharmaceuticals and pesticides…
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1986
1986
Role of propiolaldehyde and other metabolites in the pargyline inhibition of rat liver aldehyde dehydrogenase.
E. Demaster
,
F. Shirota
,
H. Nagasawa
Biochemical Pharmacology
1986
Corpus ID: 39578715
1985
1985
The metabolic fate of pargyline in rat liver microsomes.
A. Weli
,
B. Lindeke
Biochemical Pharmacology
1985
Corpus ID: 21189428
1984
1984
Inhibition of human aldehyde dehydrogenase isozymes by propiolaldehyde.
K. Ferencz-Biro
,
R. Pietruszko
Alcoholism: Clinical and Experimental Research
1984
Corpus ID: 12691387
Propiolaldehyde--a metabolite of pargyline (Shirota et al., 1979) can function as an inhibitor or as a substrate of human…
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1980
1980
Microsomal N-depropargylation of pargyline to propiolaldehyde, an irreversible inhibitor of mitochondrial aldehyde dehydrogenase.
E. Demaster
,
F. Shirota
,
H. Nagasawa
Advances in Experimental Medicine and Biology
1980
Corpus ID: 31794180
Rat liver microsomes catalyzed the conversion of pargyline (N-methyl-N-propargylbenzylamine) to propiolaldehyde, a potent…
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1980
1980
Metabolic depropargylation and its relationship to aldehyde dehydrogenase inhibition in vivo.
F. Shirota
,
E. Demaster
,
J. A. Elberling
,
H. Nagasawa
Journal of Medicinal Chemistry
1980
Corpus ID: 44694617
The relationship between metabolic depropargylation in vitro to inhibition of the low Km aldehyde dehydrogenase (AIDH) of rat…
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1979
1979
Propiolaldehyde, a pargyline metabolite that irreversibly inhibits aldehyde dehydrogenase. Isolation from a hepatic microsomal system.
F. Shirota
,
E. Demaster
,
H. Nagasawa
Journal of Medicinal Chemistry
1979
Corpus ID: 39513574
1978
1978
Inhibition of aldehyde dehydrogenase by propiolaldehyde, a possible metabolite of pargyline.
D. Eg
,
Nagasawa Ht
1978
Corpus ID: 88740388
: Pargyline (Eutonyl) inhibited aldehyde dehydrogenase (AlDH) in vivo in rats as adduced by the elevation of ethanol-derived…
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1970
1970
Prebiotic Synthesis of Propiolaldehyde and Nicotinamide
M. J. Dowler
,
W. Fuller
,
L. Orgel
,
R. Sanchez
Science
1970
Corpus ID: 35675638
We have identified propiololdehyde as a product of the action of an electric discharge on mixtures of methane and water or…
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