propiolaldehyde

Summary.Propargylamine derivatives, rasagiline and (–)deprenyl, are anti-Parkinson agents and protect neurons from cell death as… Expand

Pargyline, an antihypertensive agent and monoamine oxidase inhibitor, induces hepatic GSH depletion and hepatotoxicity in vivo in… Expand

Species differences in the metabolism of acetylenic compounds commonly used in the formulation of pharmaceuticals and pesticides… Expand

The metabolism of pargyline proceeds by way of three separate cytochrome P-450 catalyzed N-dealkylation reactions: N… Expand

Propiolaldehyde--a metabolite of pargyline (Shirota et al., 1979) can function as an inhibitor or as a substrate of human… Expand

Abstract Pargyline (N-methyl-N-propargylbenzylamine) is metabolized by the hepatic cytochrome P-450 enzymes to the reactive… Expand

Rat liver microsomes catalyzed the conversion of pargyline (N-methyl-N-propargylbenzylamine) to propiolaldehyde, a potent… Expand

 

: Pargyline (Eutonyl) inhibited aldehyde dehydrogenase (AlDH) in vivo in rats as adduced by the elevation of ethanol-derived… Expand

We have identified propiololdehyde as a product of the action of an electric discharge on mixtures of methane and water or… Expand