FAQ

proline binding

Interacting selectively and non-covalently with proline. [GOC:pm, GOC:TermGenie, PMID:7730362]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2016
024619652016

Papers overview

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2007
2007
Profilin is essential for tip growth in the moss Physcomitrella patens.
The actin cytoskeleton is critical for tip growth in plants. Profilin is the main monomer actin binding protein in plant cells… (More)
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2006
2006
Mapping active site residues in glutamate-5-kinase. The substrate glutamate and the feed-back inhibitor proline bind at overlapping sites.
Glutamate-5-kinase (G5K) catalyzes the controlling first step of proline biosynthesis. Substrate binding, catalysis and feed-back… (More)
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2003
2003
Identification of regions of the tomato gamma-glutamyl kinase that are involved in allosteric regulation by proline.
The first step of proline biosynthesis is catalyzed by gamma-glutamyl kinase (GK). To better understand the feedback inhibition… (More)
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Highly Cited
2001
Highly Cited
2001
Profilin binding to poly-L-proline and actin monomers along with ability to catalyze actin nucleotide exchange is required for viability of fission yeast.
We tested the ability of 87 profilin point mutations to complement temperature-sensitive and null mutations of the single… (More)
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2001
2001
Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases.
Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyse oxidative reactions in a range of metabolic processes including the… (More)
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1999
1999
The 2.1 A structure of a cysteine protease with proline specificity from ginger rhizome, Zingiber officinale.
A cysteine protease from ginger rhizome (GP-II) cleaves peptides and proteins with proline at the P(2) position. The unusual… (More)
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1998
1998
A conserved aspartate residue, Asp187, is important for Na+-dependent proline binding and transport by the Na+/proline transporter of Escherichia coli.
Asp187 in the Na+/proline transporter of Escherichia coli (PutP) is conserved within the Na+/solute cotransporter family… (More)
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1996
1996
A novel nonopioid action of enkephalins: competitive inhibition of the mammalian brain high affinity L-proline transporter.
The high affinity L-proline transporter (PROT) is a member of the family of Na+ (and Cl-)-dependent plasma membrane transport… (More)
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1994
1994
Elucidation of the poly-L-proline binding site in Acanthamoeba profilin I by NMR spectroscopy.
The multifunctional protein profilin is one of the most abundant proteins in the cytoplasm and is thought to regulate actin… (More)
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1992
1992
Sodium ion and proline binding sites in the Na+/proline symport carrier of Escherichia coli.
Proline binding activity of the Escherichia coli Na+/proline symport carrier is inhibited by a sulfhydryl reagent, N… (More)
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