programmed necrotic cell death

Known as: programmed cell death by necrosis 
A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors… (More)
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

necroptotic process

Broader (1)

regulated necrosis

Papers overview

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Review
2017
Review
2017
Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death.
Pyroptosis was long regarded as caspase-1-mediated monocyte death in response to certain bacterial insults. Caspase-1 is… (More)
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Review
2016
Review
2016
Programmed necrosis in inflammation: Toward identification of the effector molecules
Until recently, programmed cell death was conceived of as a single set of molecular pathways. We now know of several distinct… (More)
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2014
2014
Macromitophagy, neutral lipids synthesis, and peroxisomal fatty acid oxidation protect yeast from "liponecrosis", a previously unknown form of programmed cell death.
We identified a form of cell death called "liponecrosis." It can be elicited by an exposure of the yeast Saccharomyces cerevisiae… (More)
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Highly Cited
2013
Highly Cited
2013
TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death
Programmed necrosis is important in many (patho)physiological settings. For specific therapeutic intervention, however, a better… (More)
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Review
2011
Review
2011
Programmed necrosis: backup to and competitor with apoptosis in the immune system
Programmed cell death is essential for the development and maintenance of the immune system and its responses to exogenous and… (More)
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2011
2011
Inflammation-associated autophagy-related programmed necrotic death of human neutrophils characterized by organelle fusion events.
The most common form of neutrophil death, under both physiological and inflammatory conditions, is apoptosis. In this study, we… (More)
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Highly Cited
2011
Highly Cited
2011
zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC–MAPKs–AP-1 pathway
It is intriguing that some pan-caspase inhibitors such as zVAD-fmk (zVAD) are capable of inducing necrotic cell death in a… (More)
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Highly Cited
2010
Highly Cited
2010
Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation.
Asbestos carcinogenesis has been linked to the release of cytokines and mutagenic reactive oxygen species (ROS) from inflammatory… (More)
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2010
2010
Cyclophilin A release as a biomarker of necrotic cell death
Necroptosis is a form of programmed necrotic cell death mediated by the activity of receptor-interacting protein 1 (RIP1) kinase… (More)
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Highly Cited
2010
Highly Cited
2010
AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX.
Programmed necrosis induced by DNA alkylating agents, such as MNNG, is a caspase-independent mode of cell death mediated by… (More)
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