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prodigiosin 25C

Known as: prodigiosin 25-C 
National Institutes of Health

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Broader (1)

Prodigiosin
analogs & derivatives

Papers overview

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1998
1998
Prodigiosins uncouple mitochondrial and bacterial F-ATPases: evidence for their H+/Cl- symport activity.
Prodigiosin, metacycloprodigiosin, and prodigiosin 25-C all inhibited the acidification activity of submitochondrial and… 
1997
1997
Characterization of a series of vacuolar type H(+)-ATPase inhibitors on CTL-mediated cytotoxicity.
1997
1997
Prodigiosin 25-C and metacycloprodigiosin suppress the bone resorption by osteoclasts.
Prodigiosin 25-C and metacycloprodigiosin were found to suppress PTH-stimulated pit formation by cultured osteoclasts on bone… 
Highly Cited
1995
Highly Cited
1995
Prodigiosin 25‐C uncouples vacuolar type H+‐ATPase, inhibits vacuolar acidification and affects glycoprotein processing
1995
1995
Prodigiosin 25-C perturbs permeation of acetate in a cultured cell line.
Prodigiosin 25-C had little effect on DNA, RNA, and protein synthesis, and cellular ATP content, but the drug markedly inhibited… 
1992
1992
Effects of prodigiosin 25-C on cultured cell lines: its similarity to monovalent polyether ionophores and vacuolar type H(+)-ATPase inhibitors.
Prodigiosin 25-C inhibited the proliferation of various cultured cell lines more strongly when concanavalin A (Con A) was added… 
1992
1992
Enhancement by concanavalin A of the suppressive effect of prodigiosin 25-C on proliferation of murine splenocytes.
Proliferation of concanavalin A (Con A)-activated nylon-wool purified murine splenic T cells was increasingly suppressed by… 
Highly Cited
1990
Highly Cited
1990
Selective immunosuppression of prodigiosin 25-C and FK506 in the murine immune system.
The immunosuppressive effects of prodigiosin 25-C were studied in comparison with FK506. Both prodigiosin 25-C and FK506… 
1989
1989
Suppression of cytotoxic T cell induction in vivo by prodigiosin 25-C.
Prodigiosin 25-C (PrG25-C) was discovered as an immunosuppressant in the course of our screening for immunomodulating substances… 
Highly Cited
1986
Highly Cited
1986
Selective suppression by prodigiosin of the mitogenic response of murine splenocytes.
In the course of screening for immunomodulating substances among microbial metabolites using a triple mitogen assay system, we… 
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