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probimane

Known as: bis(4-morpholinomethyl-3,5-dioxopiperazin-1-yl)propane, bis-(4-morpholinomethyl-3,5-dioxopiperazinyl)-1-methylylethane 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

AT 2153MM 159
analogs & derivatives

Broader (1)

razoxane

Papers overview

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Review
2010
Review
2010
Cell biological manifestations of bisdioxopiperazines treatment of human tumor cell lines in culture.
British developed Bisdioxopiperazine compound (Biz compounds) {ICRF-159 or ICRF-187 (razoxane, Raz)} which was the first agent… 
2004
2004
Scavenging efects of probimane on active oxygen free radicals by electron spin resonance !
Probimane. dl--1。2-bis (4morpholine—methyl一3。 5-dioxopiperazin—l— y1) propane, is a new antitumor agent synthesized by Shanghai… 
2003
2003
Inhibition of Probimane on Lipid Peroxidation of Rabbit and Human Erythrocytes
Lipid peroxide (LPO) plays pivotal roles in the process and development of many diseases. In this work, we studied the inhibitory… 
1997
1997
Effect of probimane and doxorubicin in combination on DNA synthese and cell cycle of tumor cells
  • Y. Qi
  • 1997
  • Corpus ID: 87740677
AIM: To study the mechanism of synergistic effect of probimane (Pro) on doxorubicin (Dox) cytotoxicity. METHODS: Using typen blue… 
Review
1996
Review
1996
PHARMACOLOGICAL STUDY OF ANTINEOPLASTIC AGENT PROBIMANE
  • L. Da
  • 1996
  • Corpus ID: 100678418
Probimane is a derivative of razoxane,first synthesized in China.This paper reviews recent progress in probimane [1,2-bis(N4… 
1995
1995
Protective effect of probimane on cell calmoduline and hemolysis
  • L. Da
  • 1995
  • Corpus ID: 88330749
The comparison of the effectsof probimane with razoxane on bloodhemoglobin content,antihemolysis ability and calmoduline activity… 
1992
1992
Effect of probimane on lipid peroxidation caused by doxorubicin in rats
Probimane (AT-2153) is a dio xopiperazine compound with antineoplastic, antimetastatic and radiopotentiation activities, and ex… 
1990
1990
SHORT TERM RESULTS OF MALIGNANT LYMPHOMA TREATED WITH PROBIMANE
I From April 1987 to June 1989,28 cases of malignant lymphoma were treated With Probimane. All the cases were histologically… 
1988
1988
[Effects of bimolane and probimane on the incorporation of (3H)TdR, (3H)UR and (3H)Leu into Ehrlich ascites carcinoma cells iv vitro].
By means of liquid scintillation spectrometry. the effects of bimolane (AT-1727) and probimane (AT-2153) on the incorporation of… 
1987
1987
[Antineoplastic action and toxicity of probimane and its effect on immunologic functions in mice].
Probimane(AT-2153, MST-02), dlbis(4-morpholinomethyl-3,5-dioxopiperazin-1-yl) propane, exhibited good antitumor activities…