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probimane

Known as: bis(4-morpholinomethyl-3,5-dioxopiperazin-1-yl)propane, bis-(4-morpholinomethyl-3,5-dioxopiperazinyl)-1-methylylethane 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

AT 2153MM 159
analogs & derivatives

Broader (1)

razoxane

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Inhibitions of Several Antineoplastic Drugs on Serum Sialic Acid Levels in Mice Bearing Tumors
Six murine tumors, including ascetic tumors HepA, EC, P388 leukemia, S180 and solid tumor S180, and Lewis lung carcinoma, were… 
Review
2010
Review
2010
Anticancer activities and mechanisms of bisdioxopiperazine compounds probimane and MST-16.
Bisdioxopiperazine compounds, including ICRF-154 and razoxane (ICRF-159, Raz), are anticancer agents developed in the UK… 
2003
2003
Inhibition of Probimane on Lipid Peroxidation of Rabbit and Human Erythrocytes
Lipid peroxide (LPO) plays pivotal roles in the process and development of many diseases. In this work, we studied the inhibitory… 
1999
1999
Comparison of some antineoplastic drugs on inhibiting thrombin catalizing fibrinogen clotting in vitro.
OBJECTIVE To classify the effect of thrombin, the key enzyme which enables fibrinogen to form fibrin (fibrinogen clotting) on the… 
1994
1994
Synergistic effect of probimane on anticancer cytotoxicity of doxorubicin in vitro.
Using 3-(4,5-dimethythiazole)-2,5-diphenyltetrazolium bromide (MTT) method, the effect of probimane (Pro) on doxorubicin (Dox… 
1992
1992
Effect of probimane on lipid peroxidation caused by doxorubicin in rats
Probimane (AT-2153) is a dio xopiperazine compound with antineoplastic, antimetastatic and radiopotentiation activities, and ex… 
1991
1991
[Scavenging of probimane on semiquinone free radical formation by doxorubicin in rat heart].
Probimane, dl-bis (4-morpholin-methyl 3,5-dioxopipweazin-1-yl) propane first synthesized in China, is a dioxopiperazin compound… 
1990
1990
SHORT TERM RESULTS OF MALIGNANT LYMPHOMA TREATED WITH PROBIMANE
I From April 1987 to June 1989,28 cases of malignant lymphoma were treated With Probimane. All the cases were histologically… 
1988
1988
[Effects of bimolane and probimane on the incorporation of (3H)TdR, (3H)UR and (3H)Leu into Ehrlich ascites carcinoma cells iv vitro].
By means of liquid scintillation spectrometry. the effects of bimolane (AT-1727) and probimane (AT-2153) on the incorporation of… 
1987
1987
[Antineoplastic action and toxicity of probimane and its effect on immunologic functions in mice].
Probimane(AT-2153, MST-02), dlbis(4-morpholinomethyl-3,5-dioxopiperazin-1-yl) propane, exhibited good antitumor activities… 
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