primary cilium

A cilium found on many different cell types that is typically present in a single copy per cell. A primary cilium may have a variable array of… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
The primary cilium has recently stepped into the spotlight, as a flood of data show that this organelle has crucial roles in… (More)
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Highly Cited
2010
Highly Cited
2010
In animal cells, the primary cilium transduces extracellular signals through signaling receptors localized in the ciliary… (More)
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Highly Cited
2007
Highly Cited
2007
Primary cilia are essential for transduction of the Hedgehog (Hh) signal in mammals. We investigated the role of primary cilia in… (More)
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Highly Cited
2007
Highly Cited
2007
The mammalian cilium protrudes from the apical/lumenal surface of polarized cells and acts as a sensor of environmental cues… (More)
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Highly Cited
2007
Highly Cited
2007
Primary cilia (PC) function as microtubule-based sensory antennae projecting from the surface of many eukaryotic cells. They play… (More)
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Highly Cited
2005
Highly Cited
2005
The unanticipated involvement of several intraflagellar transport proteins in the mammalian Hedgehog (Hh) pathway has hinted at a… (More)
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Highly Cited
2005
Highly Cited
2005
Recent findings show that cilia are sensory organelles that display specific receptors and ion channels, which transmit signals… (More)
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Highly Cited
2003
Highly Cited
2003
Several proteins implicated in the pathogenesis of polycystic kidney disease (PKD) localize to cilia. Furthermore, cilia are… (More)
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Highly Cited
2003
Highly Cited
2003
The hypothesis that cell primary cilium is solely responsible for the flow-induced Ca2+ response in MDCK cells was tested by… (More)
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Highly Cited
2001
Highly Cited
2001
We tested the hypothesis that the primary cilium of renal epithelia is mechanically sensitive and serves as a flow sensor in MDCK… (More)
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