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pretubulysin

National Institutes of Health

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Oligopeptides

Papers overview

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2019
2019
Antitumoral polymeric siRNA nanoformulation and pretubulysin-based combination therapies
2019
2019
Drug delivery systems for pretubulysin-based combination chemotherapies
2017
2017
The pretubulysin-induced exposure of collagen is caused by endothelial cell retraction that results in an increased adhesion and decreased transmigration of tumor cells
Microtubule-targeting agents (MTAs) are the most widely used chemotherapeutic drugs. Pretubulysin (PT), a biosynthetic precursor… 
2014
2014
Novel Tubulin Antagonist Pretubulysin Displays Antivascular Properties In Vitro and In Vivo
Objective—Pretubulysin (PT) is a novel, synthetically accessible myxobacterial compound that acts as a tubulin-depolymerizing… 
2013
2013
Preclinical characterization of the myxobacterial compound pretubulysin as novel vascular disrupting agent
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