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presqualene pyrophosphate

Known as: presqualene diphosphate 
 
National Institutes of Health

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Related topics

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Broader (1)

Polyisoprenyl Phosphates

Papers overview

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2015
2015
Analysis of Serum Metabolic Profile by Ultra-performance Liquid Chromatography-mass Spectrometry for Biomarkers Discovery: Application in a Pilot Study to Discriminate Patients with Tuberculosis
BACKGROUND Tuberculosis (TB) is a chronic wasting inflammatory disease characterized by multisystem involvement, which can cause… Expand
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Highly Cited
2011
Highly Cited
2011
Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii.
Botryococcene biosynthesis is thought to resemble that of squalene, a metabolite essential for sterol metabolism in all… Expand
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2008
2008
Cloning, solubilization, and characterization of squalene synthase from Thermosynechococcus elongatus BP-1.
Squalene synthase (SQS) is a bifunctional enzyme that catalyzes the condensation of two molecules of farnesyl diphosphate (FPP… Expand
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2006
2006
Identification and functional characterization of a presqualene diphosphate phosphatase.
Presqualene diphosphate (PSDP) is a bioactive lipid that rapidly remodels to presqualene monophosphate (PSMP) upon cell… Expand
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2005
2005
Novel polyisoprenyl phosphates block phospholipase D and human neutrophil activation in vitro and murine peritoneal inflammation in vivo.
Leukocyte production of reactive oxygen species (ROS) is an essential component of the antimicrobial armament mounted during host… Expand
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2002
2002
Recombinant squalene synthase. Synthesis of non-head-to-tail isoprenoids in the absence of NADPH.
Squalene synthase (SQase) catalyzes two consecutive reactions in sterol biosynthesis. The first is the condensation of two… Expand
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2002
2002
Recombinant squalene synthase. A mechanism for the rearrangement of presqualene diphosphate to squalene.
Squalene synthase (SQase) catalyzes the condensation of two molecules of farnesyl diphosphate (FPP) to form presqualene… Expand
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2000
2000
Squalene synthase: steady-state, pre-steady-state, and isotope-trapping studies.
Squalene synthase catalyzes two consecutive reactions in sterol biosynthesis-the condensation of two molecules of farnesyl… Expand
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Highly Cited
1999
Highly Cited
1999
Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a 'stop' signaling switch for aspirin-triggered lipoxin A4.
It is of wide interest to understand how opposing extracellular signals (positive or negative) are translated into intracellular… Expand
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1997
1997
Polyisoprenyl phosphates in intracellular signalling
In response to environmental stimuli, leukocyte membrane remodelling generates biologically active lipids that can serve as both… Expand
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