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prespliceosome

Known as: prespliceosomal complex, prespliceosomal complex location 
A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome… 
National Institutes of Health

Papers overview

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2008
2008
Splicing Factor SPF30 Bridges an Interaction between the Prespliceosome Protein U2AF35 and Tri-small Nuclear Ribonucleoprotein Protein hPrp3*
Spliceosome assembly is a dynamic process involving the sequential recruitment and rearrangement of small nuclear… 
Highly Cited
2003
Highly Cited
2003
Spatial Organization of Protein-RNA Interactions in the Branch Site-3′ Splice Site Region during pre-mRNA Splicing in Yeast
ABSTRACT A series of efficiently spliced pre-mRNA substrates containing single 4-thiouridine residues were used to monitor RNA… 
2001
2001
A Novel Yeast U2 snRNP Protein, Snu17p, Is Required for the First Catalytic Step of Splicing and for Progression of Spliceosome Assembly
ABSTRACT We have isolated and microsequenced Snu17p, a novel yeast protein with a predicted molecular mass of 17 kDa that… 
2001
2001
New Roles for the Snp1 and Exo84 Proteins in Yeast Pre-mRNA Splicing*
The mammalian 70K protein, a component of the U1 small nuclear ribonucleoprotein involved in pre-mRNA splicing, interacts with a… 
2000
2000
An Intronic Downstream Enhancer Promotes 3′ Splice Site Usage of a Neural Cell-specific Exon*
The human nonmuscle myosin heavy chain B gene contains a 30-nucleotide alternative exon, N30, that is included in the mRNA from… 
2000
2000
Functional Cus1p Is Found with Hsh155p in a Multiprotein Splicing Factor Associated with U2 snRNA
ABSTRACT To explore the dynamics of snRNP structure and function, we have studied Cus1p, identified as a suppressor of U2 snRNA… 
Highly Cited
1997
Highly Cited
1997
Prp31p promotes the association of the U4/U6 x U5 tri-snRNP with prespliceosomes to form spliceosomes in Saccharomyces cerevisiae
The PRP31 gene encodes a factor essential for the splicing of pre-mRNA in Saccharomyces cerevisiae. Cell extracts derived from a… 
Highly Cited
1994
Highly Cited
1994
Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly
Highly purified mammalian spliceosomal complex B contains more than 30 specific protein components. We have carried out UV cross… 
1993
1993
Interactions between PRP9 and SPP91 splicing factors identify a protein complex required in prespliceosome assembly.
The PRP9 protein is a yeast splicing factor implicated in the early steps of spliceosome assembly whose sequence contains an… 
Highly Cited
1993
Highly Cited
1993
Evidence that the 60-kDa protein of 17S U2 small nuclear ribonucleoprotein is immunologically and functionally related to the yeast PRP9 splicing factor and is required for the efficient formation of…
Small nuclear ribonucleoprotein (snRNP) U2 functions in the splicing of mRNA by recognizing the branch site of unspliced mRNA… 
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